Figure 1

BBB permeability was altered in the CSF of rats infected with rabies virus. BBB permeability was assessed by measuring (A) albumin and (B) total IgG from the CSF after rabies virus infection and expressed as the concentration (μg/ml) (n = 8). Statistical significance of differences in permeability was calculated using Student’s t-test and are denoted by the symbol *p < 0.05. The CSF to serum ratios were presented in (C) for albumin and (D) for IgG. Each dot represented one individual rat.