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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: 7-oxo-DHEA enhances impaired M. tuberculosis-specific T cell responses during HIV-TB coinfection

Fig. 5

Analysis of Treg and uTreg subsets within CD4 + T cells from HIV-TB patients and HD. Recently thawed or freshly isolated PBMCs were stained and analyzed by flow cytometry. Figure shows the percentage of (a) CD4+ regulatory T cells (Tregs, CD25 + FoxP3+) and CD4+ unconventional regulatory T cells (uTregs, CD25-FoxP3+) and (b) the co-expression of the transcription factors ROR-γt or T-bet within each population. The results are plotted for HD (open circles) and HIV-TB patients (black circles). Each symbol represents an individual subject. Unpaired t test or Mann-Whitney U test, as appropriated *p < 0.05. Representative flow cytometry examples are shown

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