Fig. 3

Loss of CPEB2 reduces pulmonary myofibroblasts (MYFs) during alveologenesis. a Caveolin 1 (Cav1⁺)-immunostained images from postnatal day 3 (P3) CP2WT and CP2KO lungs with magnified images of selected areas shown in a’. The number of Cav1⁺ type I alveolar epithelial cells (AECs) was quantified from 5 mice per genotype. b,c Similar to a, pro-surfactant-C–positive (SFTPC⁺) type II AECs and αSMA⁺ MYFs counted in magnified images of selected areas shown in b’ and c’ (5 mice per genotype). d The number of αSMA⁺ MYFs counted in CP2WT and CP2KO lungs (5 mice per group) at denoted ages. Data are mean ± s.e.m., *P < 0.05 and ***P < 0.001, by Student’s t test in a-c and by two-way ANOVA and Bonferroni post-hoc test in d. Scales, 50 μm in a-d and 25 μm in a’-c’