Journal of Biomedical Science is supported by the National Science and Technology Council (NSTC), Taiwan.
Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells
Vascular endothelial cells (ECs) constantly experience fluid shear stresses generated by blood flow. Laminar flow is known to produce atheroprotective effects on ECs. Nrf2 is a transcription factor that is ess...