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792 result(s) for 'cancer' within Journal of Biomedical Science

Page 4 of 16

  1. Nasopharyngeal carcinoma (NPC) is a head and neck cancer with poor clinical outcomes and insufficient treatments ... review summarizes the mechanisms by which ANXA2 promotes cancer progression (e.g., proliferatio...

    Authors: Chang-Yu Chen, Yung-Song Lin, Chien-Ho Chen and Yin-Ju Chen
    Citation: Journal of Biomedical Science 2018 25:30
    Content type: Review Published on:

  2. Since the first discovery in 1996, the engagement of TRIM28 in distinct aspects of cellular biology has been extensively studied resulting in identification of a complex nature of TRIM28 protein. In this review, ...

    Authors: Patrycja Czerwińska, Sylwia Mazurek and Maciej Wiznerowicz
    Citation: Journal of Biomedical Science 2017 24:63
    Content type: Review Published on:

  5. Vulvar squamous cell carcinoma (VSCC) is a rare female genital neoplasm. Although numerous molecular changes have been reported in VSCC, biomarkers of clinical relevance are still lacking. On the other hand, ther...

    Authors: Aleksandra Klemba, Magdalena Kowalewska, Wojciech Kukwa, Katarzyna Tonska, Aleksandra Szybinska, Malgorzata Mossakowska, Anna Scinska, Paweł Golik, Kamil Koper, Jakub Radziszewski, Andrzej Kukwa, Anna M Czarnecka and Ewa Bartnik
    Citation: Journal of Biomedical Science 2010 17:73
    Content type: Research Published on:

  6. Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy because of their high immunomodulation ability, tropism towards inflamed and injured tissues, and their easy access and iso...

    Authors: Wei-Zhan Zhuang, Yi-Heng Lin, Long-Jyun Su, Meng-Shiue Wu, Han-Yin Jeng, Huan-Cheng Chang, Yen-Hua Huang and Thai-Yen Ling
    Citation: Journal of Biomedical Science 2021 28:28
    Content type: Review Published on:

  7. Over the past few years, long non-coding RNAs (lncRNAs) are recognized as key regulators of gene expression at chromatin, transcriptional and posttranscriptional level with pivotal roles in various biological and...

    Authors: Tse-Chun Kuo, Hsing-Jien Kung and Jing-Wen Shih
    Citation: Journal of Biomedical Science 2020 27:59
    Content type: Review Published on:

  9. This case–control study genotyped 53 single-nucleotide polymorphisms (SNPs) in FA genes in 709 patients (354 males and 355 females) with lung adenocarcinoma and in 726 cancer-free individuals (339 males and 387 f...

    Authors: Shi-Yi Yang, Chia-Ni Hsiung, Yao-Jen Li, Gee-Chen Chang, Ying-Huang Tsai, Kuan-Yu Chen, Ming-Shyan Huang, Wu-Chou Su, Yuh-Min Chen, Chao A. Hsiung, Pan-Chyr Yang, Chien-Jen Chen, Pei-Ei Wu, Jyh-Cherng Yu, Chen-Yang Shen and Huan-Ming Hsu
    Citation: Journal of Biomedical Science 2016 23:23
    Content type: Research Published on:

  10. We have previously demonstrated that cigarette smoke is associated with a significant reduction of retinoic acid in rat lungs and the formation of tracheal precancerous lesions. However, the underlying mechanism ...

    Authors: Yuan Xue, Ethan Harris, Weiqun Wang and Richard C. Baybutt
    Citation: Journal of Biomedical Science 2015 22:84
    Content type: Research Published on:

  11. The human chromosome 19 miRNA cluster (C19MC) of 43 genes is a primate-specific miRNA cluster that may have biological significance in the genetic complexity of the primate. Despite previous reports on individual...

    Authors: Phan Nguyen Nhi Nguyen, Chiu-Jung Huang, Shigeki Sugii, Soon Keng Cheong and Kong Bung Choo
    Citation: Journal of Biomedical Science 2017 24:20
    Content type: Research Published on:

  12. Gastric cancer exhibits familial clustering, and gastric cancer familial relatives (GCF) tend to present...H. pylori...infection. The study determined whether the children of gastric cancer patients (GCA) had gen...

    Authors: Yu-Ching Tsai, Wei-Hsin Hsiao, Sheng-Hsiang Lin, Hsiao-Bai Yang, Hsiu-Chi Cheng, Wei-Lun Chang, Cheng-Chan Lu and Bor-Shyang Sheu
    Citation: Journal of Biomedical Science 2015 22:16
    Content type: Research Published on:

  13. SLC34A2 with highest expressions in lung, small intestine and kidney encoded a type 2b sodium-dependent phosphate transporter (NaPi-IIb). In lung, SLC34A2...only expressed in the apical membr...

    Authors: Yu Wang, Weihan Yang, Qiang Pu, Yan Yang, Sujuan Ye, Qingping Ma, Jiang Ren, Zhixing Cao, Guoxing Zhong, Xuechao Zhang, Lunxu Liu and Wen Zhu
    Citation: Journal of Biomedical Science 2015 22:52
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2019 26:18

  14. Notch may behave as an oncogene or a tumor suppressor gene in lung cancer cells. Notch receptor undergoes cleavage by enzymes ... -secretase inhibitor, in non-small cell lung cancer (NSCLC) cells, as well as the....

    Authors: Efstathia Giannopoulou, Achilleas Nikolakopoulos, Dimitra Kotsirilou, Angeliki Lampropoulou, Sofia Raftopoulou, Evangelia Papadimitriou, Achilleas D. Theocharis, Thomas Makatsoris, Konstantinos Fasseas and Haralabos P. Kalofonos
    Citation: Journal of Biomedical Science 2015 22:98
    Content type: Research Published on:

  15. A large group of small Rab GTPases which mediate secretory and endosomal membrane transport, as well as autophagosome biogenesis, are essential components of vesicle trafficking machinery. Specific Rab protein to...

    Authors: Hong-Tai Tzeng and Yi-Ching Wang
    Citation: Journal of Biomedical Science 2016 23:70
    Content type: Review Published on:

  16. Metformin is the most commonly used first-line medicine for type II diabetes mellitus. Acting via AMP-activated protein kinase, it has been used for more than 60 years and has an outstanding safety record. Metfor...

    Authors: Shu-Man Hsieh Li, Shu-Ting Liu, Yung-Lung Chang, Ching-Liang Ho and Shih-Ming Huang
    Citation: Journal of Biomedical Science 2018 25:81
    Content type: Research Published on:

  17. Dramatic advances in immune therapy have emerged as a promising strategy in cancer therapeutics. In addition to chemotherapy and radiotherapy ... predictive biomarkers associated with positive therapeutic outcome...

    Authors: Grace Wakabayashi, Yu-Ching Lee, Frank Luh, Chun-Nan Kuo, Wei-Chiao Chang and Yun Yen
    Citation: Journal of Biomedical Science 2019 26:96
    Content type: Review Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2019 26:98

  18. Protein ubiquitination is an important mechanism for regulating the activity and levels of proteins under physiological conditions. Loss of regulation by protein ubiquitination leads to various diseases, such as

    Authors: Ming-Jer Young, Kai-Cheng Hsu, Tony Eight Lin, Wen-Chang Chang and Jan-Jong Hung
    Citation: Journal of Biomedical Science 2019 26:42
    Content type: Review Published on:

  19. TNS2 is a focal adhesions protein and a binding partner for many proteins, including the receptor tyrosine kinase Axl. Although TNS2 can bind with Axl, the details of their interactions have not been elucidated. ...

    Authors: Li-Chun Cheng, Yen-Lin Chen, An-Ning Cheng, Alan Yueh-Luen Lee, Chun-Yu Cho, Jhy-Shrian Huang and Shuang-En Chuang
    Citation: Journal of Biomedical Science 2018 25:80
    Content type: Research Published on:

  20. High DNA methylation coincided with low mRNA and protein expression levels of SOX17 in pre-treatment endoscopic biopsy from ESCC patients with poor CCRT response. SOX17 protein expression exhibited a good pred...

    Authors: I-Ying Kuo, Yu-Lin Huang, Chien-Yu Lin, Chien-Hsun Lin, Wei-Lun Chang, Wu-Wei Lai and Yi-Ching Wang
    Citation: Journal of Biomedical Science 2019 26:20
    Content type: Research Published on:

  21. Bortezomib, a proteasome inhibitor and suberoylanilide hydroxamic acid (SAHA, also known as Vorinostat), a histone deacetylase inhibitor, have been recognized as potent chemotherapeutic drugs. Bortezomib and SAHA...

    Authors: Zhuomin Huang, Shiwen Peng, Jayne Knoff, Sung Yong Lee, Benjamin Yang, Tzyy-Choou Wu and Chien-Fu Hung
    Citation: Journal of Biomedical Science 2015 22:7
    Content type: Research Published on:

  22. Recently accumulated evidence suggests that Raf kinase inhibitor protein (RKIP) participates in regulation of many signaling pathways and plays an important role in tumorigenesis and tumor metastasis. However, st...

    Authors: Fang Nie, Jianguo Cao, Jinlu Tong, Mingming Zhu, Yuan Gao and Zhihua Ran
    Citation: Journal of Biomedical Science 2015 22:56
    Content type: Research Published on:

  24. Following Milstein’s discovery, the monoclonal antibodies (mAbs) became a basic tool for biomedical science. In cancer field, since the first mAb was approved ... making of them a therapeutic option for many cancer

    Authors: S. M. Chiavenna, J. P. Jaworski and A. Vendrell
    Citation: Journal of Biomedical Science 2017 24:15
    Content type: Review Published on:

  25. Oncolytic virotherapy has currently emerged as a promising approach upon which scientists have been able to induce tumor-specific cell death in a broad spectrum of malignancies. Paramyxoviruses represent intri...

    Authors: Mohsen Keshavarz, Farid Solaymani-Mohammadi, Seyed Mohammad Miri and Amir Ghaemi
    Citation: Journal of Biomedical Science 2019 26:48
    Content type: Review Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2019 26:54

  28. Serglycin (SRGN), previously recognized as an intracellular proteoglycan involved in the storage processes of secretory granules, has recently been shown to be upregulated in several solid tumors. We have previou...

    Authors: Jing-You Guo, Chu-Hsuan Chiu, Mei-Jung Wang, Fu-An Li and Jeou-Yuan Chen
    Citation: Journal of Biomedical Science 2020 27:2
    Content type: Research Published on:

  29. Epithelial cell adhesion molecule (EpCAM) is overexpressed in solid tumors and regarded as a putative cancer stem cell marker. Here, we report ... the targeted delivery of siRNA to EpCAM positive cancer cells, ef...

    Authors: Nithya Subramanian, Jagat R Kanwar, Prasanna kumar Athalya, Narayanan Janakiraman, Vikas Khetan, Rupinder K Kanwar, Sailaja Eluchuri and Subramanian Krishnakumar
    Citation: Journal of Biomedical Science 2015 22:4
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2020 27:100

  30. Identifying the drug-deliverables that target autophagy is crucial to finding a cure for pancreatic cancer (PC), as activated autophagy is associated...in vitro and in residual PC in vivo.

    Authors: Sheeja Aravindan, Satish Kumar Ramraj, Somasundaram T Somasundaram and Natarajan Aravindan
    Citation: Journal of Biomedical Science 2015 22:28
    Content type: Research Published on:

  31. Induced pluripotency in cancer cells by ectopic expression of pluripotency-regulating ... factors may be used for disease modeling of cancers. MicroRNAs (miRNAs) are negative regulators of ... mesenchymal transit...

    Authors: Michele Sook Yuin Hiew, Han Ping Cheng, Chiu-Jung Huang, Kowit Yu Chong, Soon Keng Cheong, Kong Bung Choo and Tunku Kamarul
    Citation: Journal of Biomedical Science 2018 25:57
    Content type: Research Published on:

  34. Hypoxia in tumor niche is one of important factors to start regeneration of blood vessels, leading to increase survival, proliferation, and invasion in cancer cells. Under hypoxia microenvironment, furthermore, s...

    Authors: Chun-Chia Cheng, Siao-Syun Guan, Hao-Jhih Yang, Chun-Chao Chang, Tsai-Yueh Luo, Jungshan Chang and Ai-Sheng Ho
    Citation: Journal of Biomedical Science 2016 23:18
    Content type: Research Published on:

  35. The strong adjuvanticity associated with α-GalCer/MPL combination may to be an important tool in the development of novel and strong cancer immunotherapy.

    Authors: Fateme Gableh, Mohsen Saeidi, Shaghayegh Hemati, Kasra Hamdi, Hoorieh Soleimanjahi, Ali Gorji and Amir Ghaemi
    Citation: Journal of Biomedical Science 2016 23:16
    Content type: Research Published on:

  36. Breast cancer is considered as an increasing major life-...Andrographis paniculata..., an oriental, traditional medicinal herb commonly available in Asian countries, has a long history of treating a variety of di...

    Authors: Malabika Banerjee, Subrata Chattopadhyay, Tathagata Choudhuri, Rammohan Bera, Sanjay Kumar, Biswajit Chakraborty and Samir Kumar Mukherjee
    Citation: Journal of Biomedical Science 2016 23:40
    Content type: Research Published on:

  37. Cancer immunotherapy has revolutionized treatment and led to ... were awarded the Nobel Prize for their landmark cancer immunotherapy work regarding “cancer therapy by inhibition of negative immune regulation”...

    Authors: Austin W. T. Chiang, Hratch M. Baghdassarian, Benjamin P. Kellman, Bokan Bao, James T. Sorrentino, Chenguang Liang, Chih-Chung Kuo, Helen O. Masson and Nathan E. Lewis
    Citation: Journal of Biomedical Science 2021 28:50
    Content type: Review Published on:

  38. Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1), an inflammatory cytokine, under serum-depleted conditions which leads to suppression of lung cancer cell metastasis has been reported....

    Authors: Shan-Ying Wu, Jia-Wen Chen, Hsi-Yu Liu, Yi-Ching Wang, Yeh-Shiu Chu, Chi-Ying Huang, Kai-Ying Lan, Hsiao-Sheng Liu and Sheng-Hui Lan
    Citation: Journal of Biomedical Science 2022 29:103
    Content type: Research Published on:

  39. Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps including epithelial–...

    Authors: Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh, Jhih-Jie Tsai, Kuo-Tai Yang, Yuh-Shan Jou, Teh-Ying Chou and Tang K. Tang
    Citation: Journal of Biomedical Science 2022 29:24
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2024 31:35

  42. Extracellular communication, in other words, crosstalk between cells, has a pivotal role in the survival of an organism. This communication occurs by different methods, one of which is extracellular vesicles. ...

    Authors: Howida M. Nail, Chien-Chih Chiu, Chung-Hang Leung, Mahmoud M. M. Ahmed and Hui-Min David Wang
    Citation: Journal of Biomedical Science 2023 30:69
    Content type: Review Published on:

  43. The SCUBE [Signal peptide-Complement C1r/C1s, Uegf, Bmp1 (CUB)-Epithelial growth factor domain-containing protein] family consists of three proteins in vertebrates, SCUBE1, 2 and 3, which are highly conserved ...

    Authors: Yuh-Charn Lin, Binay K. Sahoo, Shiang-Shin Gau and Ruey-Bing Yang
    Citation: Journal of Biomedical Science 2023 30:33
    Content type: Review Published on:

  44. The NLRP3 inflammasome is an intracellular sensor and an essential component of the innate immune system involved in danger recognition. An important hallmark of inflammasome activation is the formation of a sing...

    Authors: Valentina Arrè, Rosanna Scialpi, Matteo Centonze, Gianluigi Giannelli, Maria Principia Scavo and Roberto Negro
    Citation: Journal of Biomedical Science 2023 30:90
    Content type: Review Published on:

  45. Cyclooxygenase-2(COX-2) overexpression promotes inflammation and tumorigenesis. COX-2 expression in response to diverse stimuli is tightly controlled to avoid persistent overexpression. 5-methoxyindole metabolite...

    Authors: Kenneth K Wu, Huei-Hsuan Cheng and Tzu-Ching Chang
    Citation: Journal of Biomedical Science 2014 21:17
    Content type: Review Published on:

  47. The progression and metastasis of solid tumors, including head and neck squamous cell carcinoma (HNSCC), have been related to the behavior of a small subpopulation of cancer stem cells. Here, we have established....

    Authors: Chi-Yuan Chen, Shih-Hwa Chiou, Chih-Yang Huang, Chia-Ing Jan, Shu-Chun Lin, Ming-Long Tsai and Jeng-Fan Lo
    Citation: Journal of Biomedical Science 2009 16:100
    Content type: Research Published on:

  49. Dysregulation of various cells in the tumor microenvironment (TME) causes immunosuppressive functions and aggressive tumor growth. In combination with immune checkpoint blockade (ICB), epigenetic modification-tar...

    Authors: M A A Mamun, Yu Zhang, Jin-Yuan Zhao, Dan-Dan Shen, Ting Guo, Yi-Chao Zheng, Li-Juan Zhao and Hong-Min Liu
    Citation: Journal of Biomedical Science 2023 30:60
    Content type: Review Published on:
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Journal of Biomedical Science

ISSN: 1423-0127