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222 result(s) for 'genetics' within Journal of Biomedical Science

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  1. The inward rectifier potassium current IK1 contributes to a stable resting membrane potential and phase 3 repolarization of the cardiac action potential. KCNJ2 gain-of-function mutations V93I and D172N associate ...

    Authors: Yuan Ji, Marlieke G. Veldhuis, Jantien Zandvoort, Fee L. Romunde, Marien J. C. Houtman, Karen Duran, Gijs van Haaften, Eva-Maria Zangerl-Plessl, Hiroki Takanari, Anna Stary-Weinzinger and Marcel A. G. van der Heyden
    Citation: Journal of Biomedical Science 2017 24:44
    Content type: Research Published on:

  2. Head and neck squamous carcinoma (HNSCC) is one of the most invasive types of cancer with high mortality. A previous study has indicated that low levels of let-7d and miR-205 in HNSCC patients are correlated w...

    Authors: Tomasz Kolenda, Kacper Guglas, Anna Teresiak, Renata Bliźniak and Katarzyna Lamperska
    Citation: Journal of Biomedical Science 2019 26:17
    Content type: Research Published on:

  3. The estimated glomerular filtration rate (eGFR) is a well-known measure of kidney function and is commonly used for the diagnosis and management of patients with chronic kidney disease. The inter-individual va...

    Authors: Farook Thameem, V Saroja Voruganti, John Blangero, Anthony G Comuzzie and Hanna E Abboud
    Citation: Journal of Biomedical Science 2015 22:23
    Content type: Research Published on:

  4. Kisspeptin is involved in female reproduction. This study was designed to i- estimate kisspeptin levels in women with polycystic ovary syndrome (PCOS), in comparison with controls, ii- study the correlations b...

    Authors: Fadwa S. Albalawi, Maha H. Daghestani, Mazin H. Daghestani, Abdelmoneim Eldali and Arjumand S. Warsy
    Citation: Journal of Biomedical Science 2018 25:50
    Content type: Research Published on:

  5. Tumor initiation presents a complex and unstable genomic landscape; one of the earliest hallmark events of cancer, and its progression is probably based on selection mechanisms under specific environments that...

    Authors: Robson José de Oliveira-Júnior, Carlos Ueira-Vieira, Angela Aparecida Servino Sena, Carolina Fernandes Reis, José Roberto Mineo, Luiz Ricardo Goulart and Sandra Morelli
    Citation: Journal of Biomedical Science 2016 23:22
    Content type: Research Published on:

  6. Bacteriophages are specific antagonists to bacterial hosts. These viral entities have attracted growing interest as optimal vaccine delivery vehicles. Phages are well-matched for vaccine design due to being hi...

    Authors: Leili Aghebati-Maleki, Babak Bakhshinejad, Behzad Baradaran, Morteza Motallebnezhad, Ali Aghebati-Maleki, Hamid Nickho, Mehdi Yousefi and Jafar Majidi
    Citation: Journal of Biomedical Science 2016 23:66
    Content type: Review Published on:

  7. Promyelocytic leukemia zinc finger (Plzf), a transcriptional regulator involved in a lot of important biological processes during development, has been implied to maintain neural stem cells and inhibit their d...

    Authors: Hsin-Chuan Lin, Yung-Hao Ching, Chi-Chen Huang, Ping-Chieh Pao, Yi-Hua Lee, Wen-Chang Chang, Tzu-Jen Kao and Yi-Chao Lee
    Citation: Journal of Biomedical Science 2019 26:30
    Content type: Research Published on:

  8. Alternative polyadenylation (APA) is a widespread phenomenon in the posttranscriptional regulation of gene expression that generates mRNAs with alternative 3′-untranslated regions (3’UTRs). APA contributes to ...

    Authors: Ya-Fei Xu, Ying-Qing Li, Na Liu, Qing-Mei He, Xin-Ran Tang, Xin Wen, Xiao-Jing Yang, Ying Sun, Jun Ma and Ling-Long Tang
    Citation: Journal of Biomedical Science 2018 25:74
    Content type: Research Published on:

  9. Preeclampsia (PE), as a multisystem disorder, is associated with maternal hypertension and proteinuria. Apoptosis seems to be involved in the pathophysiology of PE, although its precise pathogenic mechanisms a...

    Authors: Mahdiyeh Harati-Sadegh, Leila Kohan, Batool Teimoori, Mehrnaz Mehrabani and Saeedeh Salimi
    Citation: Journal of Biomedical Science 2019 26:92
    Content type: Research Published on:

  10. Dengue presents a wide clinical spectrum. Most patients recover following a self-limiting non-severe clinical course. A small proportion of patients progress to severe disease, mostly characterized by plasma l...

    Authors: Harsha Hapugaswatta, Pubudu Amarasena, Ranjan Premaratna, Kapila N. Seneviratne and Nimanthi Jayathilaka
    Citation: Journal of Biomedical Science 2020 27:25
    Content type: Research Published on:

  11. Thrombomodulin (TM), an integral membrane protein, has long been known for its anticoagulant activity. Recent studies showed that TM displays multifaceted activities, including the involvement in cell adhesion...

    Authors: Gang-Hui Lee, Chia-Lin Chang, Wen-Tai Chiu, Tsun-Hsien Hsiao, Po-Yuan Chen, Kuan-Chieh Wang, Cheng-Hsiang Kuo, Bing-Hung Chen, Guey-Yueh Shi, Hua-Lin Wu and Tzu-Fun Fu
    Citation: Journal of Biomedical Science 2019 26:60
    Content type: Research Published on:

  12. Jaundice is a common symptom of inherited or acquired liver diseases or a manifestation of diseases involving red blood cell metabolism. Recent progress has elucidated the molecular mechanisms of bile metaboli...

    Authors: Huey-Ling Chen, Shang-Hsin Wu, Shu-Hao Hsu, Bang-Yu Liou, Hui-Ling Chen and Mei-Hwei Chang
    Citation: Journal of Biomedical Science 2018 25:75
    Content type: Review Published on:

  13. Cisplatin (cis-diamminedichloroplatinum II, CDDP) is one of the most effective chemotherapeutic agents. However, its clinical use is limited due to the severe side effects, including nephrotoxicity and acute k...

    Authors: Vladislav Volarevic, Bojana Djokovic, Marina Gazdic Jankovic, C. Randall Harrell, Crissy Fellabaum, Valentin Djonov and Nebojsa Arsenijevic
    Citation: Journal of Biomedical Science 2019 26:25
    Content type: Review Published on:

  15. Cholinergic hypothesis of Alzheimer’s disease (AD) is based on the findings that a reduced and/or perturbed cholinergic activity in the central nervous system correlates with cognitive decline in patients with...

    Authors: Alice Hálová, Jana Janoutová, Laura Ewerlingová, Vladimír Janout, Ondřej Bonczek, Tomáš Zeman, Tereza Gerguri, Vladimir J. Balcar and Omar Šerý
    Citation: Journal of Biomedical Science 2018 25:41
    Content type: Research Published on:

  16. Human papillomavirus (HPV) is the most common sexually transmitted virus in women worldwide. The persistence of the virus may cause warts that are considered benign lesions and low or high grade intraepithelia...

    Authors: Nádia Calvo Martins Okuyama, Fernando Cezar-dos-Santos, Érica Romão Pereira, Kleber Paiva Trugilo, Guilherme Cesar Martelossi Cebinelli, Michelle Mota Sena, Ana Paula Lombardi Pereira, Adriano Martin Felis Aranome, Luis Fernando Lasaro Mangieri, Rodolfo Sanches Ferreira, Maria Angelica Ehara Watanabe and Karen Brajão de Oliveira
    Citation: Journal of Biomedical Science 2018 25:69
    Content type: Research Published on:

  17. Dysregulated long noncoding RNAs (lncRNAs) are involved in the development of tumor. Aberrant methylation is one of the most frequent epigenetic alterations that regulate the expression of genes. The aim of th...

    Authors: Wenxia Meng, Weina Cui, Lei Zhao, Weiwei Chi, Huan Cao and Baoshan Wang
    Citation: Journal of Biomedical Science 2019 26:13
    Content type: Research Published on:

  18. Human enteroviruses contain over 100 serotypes. We have routinely conducted enterovirus surveillance in northern Taiwan; but about 10% of isolates could not be serotyped using traditional assays. Next-generati...

    Authors: Yeh-Sheng Chien, Shu-Ting Luo, Kuo-Chien Tsao, Yhu-Chering Huang, Wan-Yu Chung, Yu-Chieh Liao, Yi Tan, Suman R. Das and Min-Shi Lee
    Citation: Journal of Biomedical Science 2019 26:49
    Content type: Research Published on:

  19. Adiponectin levels have been shown to be associated with colorectal cancer (CRC). Furthermore, a newly identified adiponectin receptor, T-cadherin, has been associated with plasma adiponectin levels. Therefore...

    Authors: Jongkeun Park, Injung Kim, Keum Ji Jung, Soriul Kim, Sun Ha Jee and Sungjoo Kim Yoon
    Citation: Journal of Biomedical Science 2015 22:73
    Content type: Research Published on:
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Journal of Biomedical Science

ISSN: 1423-0127