Skip to main content

Articles

356 result(s) for 'screening test' within Journal of Biomedical Science

Page 4 of 8

  1. Taurine plays an important role in reducing physiological stress. Recent studies indicated that taurine may serve as an anti-obesity agent at the cellular level. This study characterizes taurine’s potential an...

    Authors: Hye Min Kim, Chang-Hee Do and Dong Hee Lee
    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S33
    Content type: Review Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  2. Interleukin 12B (IL12B) gene polymorphisms have been linked to several inflammatory diseases, but their role in the development of Graves ophthalmopathy (GO) in Graves disease (GD) patients is unclear. The purpos...

    Authors: Yu-Huei Liu, Ching-Chu Chen, Li-Ling Liao, Lei Wan, Chang-Hai Tsai and Fuu-Jen Tsai
    Citation: Journal of Biomedical Science 2012 19:97
    Content type: Research Published on:

  3. Amyotrophic lateral sclerosis (ALS) associated with TAR DNA-binding protein 43 (TDP-43) aggregation has been considered as a lethal and progressive motor neuron disease. Recent studies have shown that both C-t...

    Authors: Yu-Ling Tseng, Po-Chao Lu, Chi-Chang Lee, Ruei-Yu He, Yung-An Huang, Yin-Chen Tseng, Ting-Jen Rachel Cheng, Joseph Jen-Tse Huang and Jim-Min Fang
    Citation: Journal of Biomedical Science 2023 30:27
    Content type: Research Published on:

  4. A recessive mutation “c” in the Mexican axolotl, Ambystoma mexicanum, results in the failure of normal heart development. In homozygous recessive embryos, the hearts do not have organized myofibrils and fail to b...

    Authors: Andrei Kochegarov, Ashley Moses, William Lian, Jessica Meyer, Michael C Hanna and Larry F Lemanski
    Citation: Journal of Biomedical Science 2013 20:20
    Content type: Research Published on:

  5. Most filarial nematodes contain Wolbachia symbionts. The purpose of this study was to examine the effects of doxycycline on gene expression in Wolbachia and adult female Brugia malayi.

    Authors: Ramakrishna U Rao, Yuefang Huang, Sahar Abubucker, Michael Heinz, Seth D Crosby, Makedonka Mitreva and Gary J Weil
    Citation: Journal of Biomedical Science 2012 19:21
    Content type: Research Published on:

  6. N-linked glycosylation is one of the most abundant posttranslational modifications of membrane-bound proteins in eukaryotes and affects a number of biological activities, including protein biosynthesis, protein.....

    Authors: Ying-Nai Wang, Heng-Huan Lee, Jennifer L. Hsu, Dihua Yu and Mien-Chie Hung
    Citation: Journal of Biomedical Science 2020 27:77
    Content type: Review Published on:

  7. The Brugada syndrome is characterized by ST segment elevation in the right precodial leads V1-V3 on surface ECG accompanied by episodes of ventricular fibrillation causing syncope or even sudden death. The mol...

    Authors: Chia-Hsiang Hsueh, Wen-Pin Chen, Jiunn-Lee Lin, Chia-Ti Tsai, Yen-Bin Liu, Jyh-Ming Juang, Hsuan-Ming Tsao, Ming-Jai Su and Ling-Ping Lai
    Citation: Journal of Biomedical Science 2009 16:23
    Content type: Research Published on:

  9. β-Lapachone has antitumor and wound healing-promoting activities. To address the potential influences of various chemicals on heart development of zebrafish embryos, we previously treated zebrafish embryos wit...

    Authors: Yi-Ting Wu, Che Yi Lin, Ming-Yuan Tsai, Yi-Hua Chen, Yu-Fen Lu, Chang-Jen Huang, Chao-Min Cheng and Sheng-Ping L Hwang
    Citation: Journal of Biomedical Science 2011 18:70
    Content type: Research Published on:

  11. Bioactive materials have now raised considerable attention for the treatment of osteoarthritis (OA), such as knee OA, rheumatoid OA, and temporomandibular joint (TMJ) OA. TMJ-OA is a common disease associated ...

    Authors: Bou-Yue Peng, Abhinay Kumar Singh, Ching-Yu Tsai, Chun-Hao Chan, Yue-Hua Deng, Chi-Ming Wu, Yen-Ru Chou, Wen Tsao, Chia-Yu Wu and Win-Ping Deng
    Citation: Journal of Biomedical Science 2023 30:77
    Content type: Research Published on:

  12. Human enteroviruses contain over 100 serotypes. We have routinely conducted enterovirus surveillance in northern Taiwan; but about 10% of isolates could not be serotyped using traditional assays. Next-generati...

    Authors: Yeh-Sheng Chien, Shu-Ting Luo, Kuo-Chien Tsao, Yhu-Chering Huang, Wan-Yu Chung, Yu-Chieh Liao, Yi Tan, Suman R. Das and Min-Shi Lee
    Citation: Journal of Biomedical Science 2019 26:49
    Content type: Research Published on:

  13. The diastolic oscillatory after-potential Vos and pre-potential ThVos play an essential role in the pacemaker mechanism of sino-atrial node (SAN). The aim of this study was to investigate whether these oscillator...

    Authors: Mario Vassalle, John N Catanzaro, Michael P Nett and Marcello Rota
    Citation: Journal of Biomedical Science 2009 16:101
    Content type: Research Published on:

  14. MSP58 is a nucleolar protein associated with rRNA transcription and cell proliferation. Its mechanism of translocation into the nucleus or the nucleolus, however, is not entirely known. In order to address thi...

    Authors: Chuan-Pin Yang, Chi-Wu Chiang, Chang-Han Chen, Yi-Chao Lee, Mei-Hsiang Wu, Yi-Huan Tsou, Yu-San Yang, Wen-Chang Chang and Ding-Yen Lin
    Citation: Journal of Biomedical Science 2015 22:33
    Content type: Research Published on:

    The Erratum to this article has been published in Journal of Biomedical Science 2015 22:60

  15. Sudden cardiac death (SCD) is a sudden, unexpected death that is caused by the loss of heart function. While SCD affects many patients suffering from coronary artery diseases (CAD) and heart failure (HF), a co...

    Authors: Junaida Osman, Shing Cheng Tan, Pey Yee Lee, Teck Yew Low and Rahman Jamal
    Citation: Journal of Biomedical Science 2019 26:39
    Content type: Review Published on:

  16. Whether microgravity might influence tumour growth and carcinogenesis is still an open issue. It is not clear also if and how normal and transformed cells are differently solicited by microgravity. The present...

    Authors: Paola Cuccarolo, Francesca Barbieri, Monica Sancandi, Silvia Viaggi and Paolo Degan
    Citation: Journal of Biomedical Science 2010 17:63
    Content type: Research Published on:

  17. Pregnancy associated plasma protein-A (PAPP-A) plays an integral role in breast cancer (BC), especially triple negative breast cancer (TNBC). This subtype accounts for the most aggressive BC, possesses high tu...

    Authors: Arpita Poddar, Farah Ahmady, Sushma R. Rao, Revati Sharma, George Kannourakis, Prashanth Prithviraj and Aparna Jayachandran
    Citation: Journal of Biomedical Science 2024 31:23
    Content type: Review Published on:

  18. Targeted therapy of human cancers is an attractive approach and has been investigated with limited success. We have developed novel cytotoxic agents for targeted therapy of human cancers based on the extracell...

    Authors: Derek V Chan, Rahul Sharma, Chiao-Ying A Ju, Steve R Roffler and Shyr-Te Ju
    Citation: Journal of Biomedical Science 2013 20:16
    Content type: Research Published on:

  19. K1 capsular polysaccharide (CPS)-associated Klebsiella pneumoniae is the primary cause of pyogenic liver abscesses (PLA) in Asia. Patients with PLA often have serious complications, ultimately leading to a mortal...

    Authors: I-Fan Tu, Tzu-Lung Lin, Feng-Ling Yang, I-Ming Lee, Wei-Lin Tu, Jiahn-Haur Liao, Tzu-Ping Ko, Wen-Jin Wu, Jia-Tsrong Jan, Meng-Ru Ho, Ching-Yi Chou, Andrew H.-J. Wang, Chung-Yi Wu, Jin-Town Wang, Kai-Fa Huang and Shih-Hsiung Wu
    Citation: Journal of Biomedical Science 2022 29:9
    Content type: Research Published on:

  20. Increasing evidences have suggested an important role of microRNAs (miRNAs) in regulating cell death processes including NETosis and apoptosis. Dysregulated expression of miRNAs and increased formation of neut...

    Authors: Yu-Tung Hsieh, Yu-Chi Chou, Pin-Yu Kuo, Hung-Wen Tsai, Yi-Ting Yen, Ai-Li Shiau and Chrong-Reen Wang
    Citation: Journal of Biomedical Science 2022 29:62
    Content type: Research Published on:

  21. Breast cancer is one of the most common malignancies that pose a serious threat to women's health. Reprogramming of energy metabolism is a major feature of the malignant transformation of breast cancer. Compar...

    Authors: Shiliang Xu, Lingxia Wang, Yuexin Zhao, Tong Mo, Bo Wang, Jun Lin and Huan Yang
    Citation: Journal of Biomedical Science 2024 31:25
    Content type: Review Published on:

  22. Mitochondria are sub-cellular organelles that produce adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS). As suggested over 70 years ago by Otto Warburg and recently confirmed with molecul...

    Authors: Anna M Czarnecka, Jerzy S Czarnecki, Wojciech Kukwa, Francesco Cappello, Anna Ścińska and Andrzej Kukwa
    Citation: Journal of Biomedical Science 2010 17:31
    Content type: Review Published on:

  24. Heat shock protein 27 (HSP27) is overexpressed during pulmonary fibrosis (PF) and exacerbates PF; however, the upregulation of HSP27 during PF and the therapeutic strategy of HSP27 inhibition is not well eluci...

    Authors: Seulgi Jeon, Hee Jin, Jin-Mo Kim, Youmin Hur, Eun Joo Song, Yoon-Jin Lee, Younghwa Na, Jaeho Cho and Yun-Sil Lee
    Citation: Journal of Biomedical Science 2023 30:2
    Content type: Research Published on:

  25. Ticks are vectors of various pathogens, including tick-borne encephalitis virus causing TBE and bacteria such as Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum causing e.g. viral-bacterial co-infec...

    Authors: Marta Dobrzyńska, Anna Moniuszko-Malinowska, Piotr Radziwon, Sławomir Pancewicz, Agnieszka Gęgotek and Elżbieta Skrzydlewska
    Citation: Journal of Biomedical Science 2024 31:28
    Content type: Research Published on:

  26. Dysmorphogenesis and multiple organ defects are well known in zebrafish (Danio rerio) embryos with T-box transcription factor 5 (tbx5) deficiencies, mimicking human Holt-Oram syndrome.

    Authors: Tzu-Chun Tsai, Jen-Kann Lu, Sie-Lin Choo, Shu-Yu Yeh, Ren-Bing Tang, Hsin-Yu Lee and Jen-Her Lu
    Citation: Journal of Biomedical Science 2012 19:63
    Content type: Research Published on:

  27. Electrical impulses from cardiac pacemaker cardiomyocytes initiate cardiac contraction and blood pumping and maintain life. Abnormal electrical impulses bring patients with low heart rates to cardiac arrest. T...

    Authors: Chih-Min Liu, Yi-Chun Chen and Yu-Feng Hu
    Citation: Journal of Biomedical Science 2023 30:74
    Content type: Review Published on:

  28. Cancer-specific adoptive T cell therapy has achieved successful milestones in multiple clinical treatments. However, the commercial production of cancer-specific T cells is often hampered by laborious cell cul...

    Authors: Yi-Jou Chen, Michael Chen, Tian-Lu Cheng, Yi-Shan Tsai, Chang-Hung Wang, Che-Yi Chen, Tung-Yun Wu, Shey-Cherng Tzou, Kai-Hung Wang, Jing-Jy Cheng, An-Pei Kao, Shyr-Yi Lin and Kuo-Hsiang Chuang
    Citation: Journal of Biomedical Science 2023 30:35
    Content type: Research Published on:

  30. Mesenchymal stem cells (MSCs) exhibit two bidirectional immunomodulatory abilities: proinflammatory and anti-inflammatory regulatory effects. Long noncoding RNAs (lncRNAs) have important functions in the immun...

    Authors: Jiajie Lin, Zhongyu Xie, Zhaoqiang Zhang, Ming Li, Guiwen Ye, Wenhui Yu, Jinteng Li, Feng Ye, Zepeng Su, Yunshu Che, Peitao Xu, Chenying Zeng, Peng Wang, Yanfeng Wu and Huiyong Shen
    Citation: Journal of Biomedical Science 2022 29:73
    Content type: Research Published on:

  31. Oxidative stress induced by the production of reactive oxygen species may play a critical role in the stimulation of HIV replication and the development of immunodeficiency. This study was conducted as there a...

    Authors: DR Suresh, Vamseedhar Annam, K Pratibha and BV Maruti Prasad
    Citation: Journal of Biomedical Science 2009 16:61
    Content type: Research Published on:

  32. Gaining further insights into SARS-CoV-2 routes of infection and the underlying pathobiology of COVID-19 will support the design of rational treatments targeting the life cycle of the virus and/or the adverse ...

    Authors: Ioannis P. Trougakos, Kimon Stamatelopoulos, Evangelos Terpos, Ourania E. Tsitsilonis, Evmorfia Aivalioti, Dimitrios Paraskevis, Efstathios Kastritis, George N. Pavlakis and Meletios A. Dimopoulos
    Citation: Journal of Biomedical Science 2021 28:9
    Content type: Review Published on:

  33. Cathepsin S (CTSS) is a cysteine protease that played diverse roles in immunity, tumor metastasis, aging and other pathological alterations. At the cellular level, increased CTSS levels have been associated wi...

    Authors: Hao-Wei Lee, Szu-Jung Chen, Kuen-Jer Tsai, Kuei-Sen Hsu, Yi-Fan Chen, Chih-Hua Chang, Hsiao-Han Lin, Wen-Yun Hsueh, Hsing-Pang Hsieh, Yueh-Feng Lee, Huai-Chueh Chiang and Jang-Yang Chang
    Citation: Journal of Biomedical Science 2024 31:46
    Content type: Research Published on:

  34. Parkinson's disease (PD) is a neurodegenerative disorder. The diagnosis of Parkinsonism is challenging because currently none of the clinical tests have been proven to help in diagnosis. PD may produce charact...

    Authors: Shiek SSJ Ahmed, Winkins Santosh, Suresh Kumar and Hema T Thanka Christlet
    Citation: Journal of Biomedical Science 2009 16:63
    Content type: Research Published on:

  35. Sudden cardiac death (SCD) is the clinical outcome of a lethal arrhythmia that can develop on the background of unrecognized channelopathies or cardiomyopathies. Several susceptibility genes have been identifi...

    Authors: Vincenzo Lariccia, Annamaria Assunta Nasti, Federica Alessandrini, Mauro Pesaresi, Santo Gratteri, Adriano Tagliabracci and Salvatore Amoroso
    Citation: Journal of Biomedical Science 2014 21:58
    Content type: Research Published on:

  36. Down syndrome (DS) is one of the commonest disorders with huge medical and social cost. DS is associated with number of phenotypes including congenital heart defects, leukemia, Alzeihmer’s disease, Hirschsprun...

    Authors: Ambreen Asim, Ashok Kumar, Srinivasan Muthuswamy, Shalu Jain and Sarita Agarwal
    Citation: Journal of Biomedical Science 2015 22:41
    Content type: Review Published on:

  38. Growth factor signaling plays a pivotal role in diverse biological functions, such as cell growth, apoptosis, senescence, and migration and its deregulation has been linked to various human diseases. Akt kinas...

    Authors: Pei-Jane Tsai, Yi-Hsin Lai, Rajesh Kumar Manne, Yau-Sheng Tsai, Dos Sarbassov and Hui-Kuan Lin
    Citation: Journal of Biomedical Science 2022 29:76
    Content type: Review Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2023 30:7

  39. Detection of cholangiocarcinoma (CCA) remains a diagnostic challenge. We established diagnostic peptide biomarkers in bile and urine based on capillary electrophoresis coupled to mass spectrometry (CE-MS) to d...

    Authors: Torsten Voigtländer, Jochen Metzger, Holger Husi, Martha M. Kirstein, Martin Pejchinovski, Agnieszka Latosinska, Maria Frantzi, William Mullen, Thorsten Book, Harald Mischak and Michael P. Manns
    Citation: Journal of Biomedical Science 2020 27:13
    Content type: Research Published on:

  40. Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps including epithelial–mesenchymal transition (EMT) process. Centrosome is an organelle that functions as the ma...

    Authors: Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh, Jhih-Jie Tsai, Kuo-Tai Yang, Yuh-Shan Jou, Teh-Ying Chou and Tang K. Tang
    Citation: Journal of Biomedical Science 2022 29:24
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2024 31:35

  41. Shikonin, a phytochemical purified from Lithospermum erythrorhizon, has been shown to confer diverse pharmacological activities, including accelerating granuloma formation, wound healing, anti-inflammation and ot...

    Authors: Hui-Ming Chen, Pi-Hsueh Wang, Kandan Aravindaram, Yun-Hsiang Chen, Hsiu-Hui Yu, Wen-Chin Yang and Ning-Sun Yang
    Citation: Journal of Biomedical Science 2012 19:42
    Content type: Research Published on:

  43. At least one-third of epithelial ovarian cancers are associated with the development of ascites containing heterogeneous cell populations, including tumor cells, inflammatory cells, and stromal elements. The c...

    Authors: Chih-Ming Ho, Shwu-Fen Chang, Chih-Chiang Hsiao, Tsai-Yen Chien and Daniel Tzu-Bi Shih
    Citation: Journal of Biomedical Science 2012 19:23
    Content type: Research Published on:

  44. Daidzein, a phytoestrogen found in isoflavone, is known to exert neurotrophic and neuroprotective effects on the nervous system. Using primary rat dorsal root ganglion (DRG) neuronal cultures, we have examined...

    Authors: Shih-Hung Yang, Chih-Chen Liao, Ying Chen, Jhih-Pu Syu, Chung-Jiuan Jeng and Seu-Mei Wang
    Citation: Journal of Biomedical Science 2012 19:80
    Content type: Research Published on:

  45. We aimed to examine the expression level of Nucleophosmin (NPM1) protein in colon cancer tissues and to investigate the potential role of NPM1 in the regulation of cell migration and invasiveness.

    Authors: Yan Liu, Fei Zhang, Xiao-fang Zhang, Li-sha Qi, Lei Yang, Hua Guo and Ning Zhang
    Citation: Journal of Biomedical Science 2012 19:53
    Content type: Research Published on:

  46. Autophagy has been shown recently to play an important role in the intracellular survival of several pathogenic bacteria. In this study, we investigated the effect of a novel small-molecule autophagy-inducing ...

    Authors: Hao-Chieh Chiu, Shilpa Soni, Samuel K Kulp, Heather Curry, Dasheng Wang, John S Gunn, Larry S Schlesinger and Ching-Shih Chen
    Citation: Journal of Biomedical Science 2009 16:110
    Content type: Research Published on:

  47. The activation of the unfolded protein response (UPR) is closely linked to the pathogenesis of renal injuries. However, the role of XBP1, a crucial regulator of adaptive UPR, remains unclear during the transit...

    Authors: Jia-Huang Chen, Chia-Hsien Wu, Jia-Rong Jheng, Chia-Ter Chao, Jenq-Wen Huang, Kuan-Yu Hung, Shing-Hwa Liu and Chih-Kang Chiang
    Citation: Journal of Biomedical Science 2022 29:46
    Content type: Research Published on:

  48. Columbianadin (CBN) is one of the main coumarin constituents isolated from Angelica pubescens. The pharmacological value of CBN is well demonstrated, especially in the prevention of several cancers and analgesic ...

    Authors: Shaw-Min Hou, Chih-Wei Hsia, Cheng-Lin Tsai, Chih-Hsuan Hsia, Thanasekaran Jayakumar, Marappan Velusamy and Joen-Rong Sheu
    Citation: Journal of Biomedical Science 2020 27:60
    Content type: Research Published on:

  49. Patients with colon adenocarcinoma (COAD) exhibit significant heterogeneity in overall survival. The current tumor-node-metastasis staging system is insufficient to provide a precise prediction for prognosis. ...

    Authors: Jing Lu, Francesco Annunziata, Dovydas Sirvinskas, Omid Omrani, Huahui Li, Seyed Mohammad Mahdi Rasa, Anna Krepelova, Lisa Adam and Francesco Neri
    Citation: Journal of Biomedical Science 2022 29:81
    Content type: Research Published on:

  50. Increased lipid accumulation and mitochondrial dysfunction within skeletal muscle have been shown to be strongly associated with insulin resistance. However, the role of mitofusion-2 (MFN2), a key factor in mi...

    Authors: Xuemei Zhang, Chao Wang, Guangyao Song, Kexin Gan, Dexian Kong, Qian Nie and Luping Ren
    Citation: Journal of Biomedical Science 2013 20:45
    Content type: Research Published on:
Submit manuscript

Annual Journal Metrics

  • 2022 Citation Impact
    11.0 - 2-year Impact Factor
    10.9 - 5-year Impact Factor
    2.367 - SNIP (Source Normalized Impact per Paper)
    2.520 - SJR (SCImago Journal Rank)

    2023 Speed
    14 days submission to first editorial decision for all manuscripts (Median)
    107 days submission to accept (Median)

    2023 Usage 
    1,698,723 downloads
    3,813 Altmetric mentions 

Journal of Biomedical Science

ISSN: 1423-0127