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Volume 17 Supplement 1

Taurine - a wonder molecule. Proceedings of the 17th International Taurine Conference

Proceedings

Edited by Jang-Yen Wu, Stephen W Schaffer and Junichi Azuma

17th International Meeting of Taurine.

Fort Lauderdale, FL, USA14-19 December 2009

  1. Taurine demonstrates multiple cellular functions including a central role as a neurotransmitter, as a trophic factor in CNS development, in maintaining the structural integrity of the membrane, in regulating c...

    Authors: Jang-Yen Wu and Howard Prentice

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S1

    Content type: Research

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  2. Taurine (aminoethane sulfonic acid) is an ubiquitous compound, found in very high concentrations in heart and muscle. Although taurine is classified as an amino acid, it does not participate in peptide bond fo...

    Authors: Stephen W Schaffer, Chian Ju Jong, Ramila KC and Junichi Azuma

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S2

    Content type: Research

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  4. Taurine participates in a number of different physiologic and biologic processes in the kidney, often reflected by urinary excretion patterns. The kidney is key to aspects of taurine body pool size and homeost...

    Authors: Russell W Chesney, Xiaobin Han and Andrea B Patters

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S4

    Content type: Research

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  5. Although taurine and glutamate are the most abundant amino acids conducting neural signals in the central nervous system, the communication between these two neurotransmitters is largely unknown. This study ex...

    Authors: Simon Bulley and Wen Shen

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S5

    Content type: Research

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  6. Taurine (T) was first noted as beneficial for stroke and cardiovascular diseases (CVD) prevention in genetic rat models, stroke-prone spontaneously hypertensive rats (SHRSP). The preventive mechanisms of T wer...

    Authors: Yukio Yamori, Takashi Taguchi, Atsumi Hamada, Kazuhiro Kunimasa, Hideki Mori and Mari Mori

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S6

    Content type: Research

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  7. Arsenic exposure induces overproduction of reactive nitrogen species (RNS) in brain tissue and results in nucleic acid damage to the nerve cells. The 8-nitroguanine is one of the major products formed by the r...

    Authors: Ning Ma, Mikio Sasoh, Shosuke Kawanishi, Hiromichi Sugiura and Fengyuan Piao

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S7

    Content type: Review

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  8. The fragile X mouse model shows an increase in seizure susceptibility, indicating an involvement of the GABAergic system via an alteration in cellular excitability. In the brain, we have previously described a...

    Authors: Abdeslem El Idrissi, Xin Yan, Francoise Sidime and William L’Amoreaux

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S8

    Content type: Review

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  9. It has been demonstrated that taurine is one of the most abundant free amino acids in the male reproductive system, and can be biosynthesized by male reproductive organs. But the effect of taurine on male repr...

    Authors: Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lv, Shumei Lin and Jianmin Hu

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S9

    Content type: Review

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  11. Pancreatic β-cells release insulin via an electrogenic response triggered by an increase in plasma glucose concentrations. The critical plasma glucose concentration has been determined to be ~3 mM, at which ti...

    Authors: William J L’Amoreaux, Christina Cuttitta, Allison Santora, Jonathan F Blaize, Janto Tachjadi and Abdeslem El Idrissi

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S11

    Content type: Review

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  12. Acute ethanol administration leads to massive apoptotic neurodegeneration in the developing central nervous system. We studied whether taurine is neuroprotective in ethanol-induced apoptosis in the mouse cereb...

    Authors: Andrey G Taranukhin, Elena Y Taranukhina, Pirjo Saransaari, Irina M Podkletnova, Markku Pelto-Huikko and Simo S Oja

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S12

    Content type: Review

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  13. Taurine and zinc exert neurotrophic effects in the central nervous system. Current studies demonstrate that Na+/Cl- dependent neurotransmitter transporters, similar to that of taurine, are modulated by micromolar...

    Authors: Sonia Nusetti, Mary Urbina and Lucimey Lima

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S13

    Content type: Review

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  14. Taurine is one of the most abundant free amino acids especially in excitable tissues, with wide physiological actions. Chronic supplementation of taurine in drinking water to mice increases brain excitability ...

    Authors: William J L’Amoreaux, Alexandra Marsillo and Abdeslem El Idrissi

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S14

    Content type: Review

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  15. Fragile X Syndrome is the most common known genetic cause of autism. The Fmr1-KO mouse, lacks the fragile X mental retardation protein (FMRP), and is used as a model of the syndrome. The core behavioral deficits ...

    Authors: Abdeslem El Idrissi, Lorenz S Neuwirth and William L’Amoreaux

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S15

    Content type: Review

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  16. Poly(ADP-ribose) is a NAD+-requiring, DNA-repairing, enzyme playing a central role in pancreatic β-cell death and in the development of endothelial dysfunction in humans and experimental animals. PARP activation ...

    Authors: Kashyap G Pandya, Maulik R Patel and Cesar A Lau-Cam

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S16

    Content type: Review

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  17. Taurine is a free amino acid present in high concentrations in a variety of organs of mammalians. As an antioxidant, taurine has been found to protect cells against oxidative stress, but the underlying mechani...

    Authors: Chunliu Pan, Grace S Giraldo, Howard Prentice and Jang-Yen Wu

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S17

    Content type: Review

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  18. Both taurine, an inhibitory neurotransmitter and granulocyte colony-stimulating factor (G-CSF), a growth factor, possess neuroprotective and neurotrophic properties in vitro. However, the mechanisms of their u...

    Authors: Chunliu Pan, Amit Gupta, Howard Prentice and Jang-Yen Wu

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S18

    Content type: Review

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  19. To assess the effect of taurine on lipopolysaccharide (LPS)-induced lung inflammation, oxidative stress and apoptosis, female Golden Syrian hamsters were intratracheally instilled with bacterial LPS (0.02 mg i...

    Authors: Tapan M Bhavsar, Sanket N Patel and Cesar A Lau-Cam

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S19

    Content type: Review

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  20. Taurine, a sulfur-containing β-amino acid, is highly contained in heart and skeletal muscle. Taurine has a variety of biological actions, such as ion movement, calcium handling and cytoprotection in the cardia...

    Authors: Takashi Ito, Shohei Oishi, Mika Takai, Yasushi Kimura, Yoriko Uozumi, Yasushi Fujio, Stephen W Schaffer and Junichi Azuma

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S20

    Content type: Review

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  21. Since taurine (T) administration was proven to decrease blood pressure (BP) and stroke mortality in stroke-prone spontaneously hypertension rates (SHRSP) in the 1980’s and our WHO-coordinated CARDIAC (Cardiova...

    Authors: Yukio Yamori, Takashi Taguchi, Hideki Mori and Mari Mori

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S21

    Content type: Review

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  22. Perinatal taurine depletion and high sugar diets blunted baroreflex function and heightens sympathetic nerve activity in adult rats. Cardiac ischemia/reperfusion also produces these disorders and taurine treat...

    Authors: Supaporn Kulthinee, J Michael Wyss, Dusit Jirakulsomchok and Sanya Roysommuti

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S22

    Content type: Review

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  23. The mitochondrial pH gradient across the inner-membrane is stabilised by buffering of the matrix. A low-molecular mass buffer compound has to be localised in the matrix to maintain its alkaline pH value. Tauri...

    Authors: Svend Høime Hansen, Mogens Larsen Andersen, Claus Cornett, Robert Gradinaru and Niels Grunnet

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S23

    Content type: Review

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  25. The β-amino acid, taurine, is a nutritional requirement in some species. In these species, the depletion of intracellular stores of taurine leads to the development of severe organ dysfunction. The basis under...

    Authors: Chian Ju Jong, Takashi Ito, Mahmood Mozaffari, Junichi Azuma and Stephen Schaffer

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S25

    Content type: Review

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  26. ER stress is a strong indicator of whether or not a cell is undergoing physiological stress. C. elegans is a practical system of characterizing the effect of ER stress at the in vivo or organismal level.

    Authors: Hye Min Kim, Chang-Hee Do and Dong Hee Lee

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S26

    Content type: Review

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  27. Adiponectin greatly stimulated the expression of matrix metalloproteinases (MMPs) in fibroblast-like synoviocytes (FLSs) as did IL-1β. We wondered whether taurine chloramine (TauCl) inhibits the production of ...

    Authors: Kyoung Soo Kim, Hyun-Mi Choi, Da Hee Oh, Chaekyun Kim, Jin Seok Jeong, Myung Chul Yoo and Hyung-In Yang

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S27

    Content type: Review

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  28. Cisplatin is a commonly used chemotherapeutic agent that has a major limitation because of its nephrotoxicity. We have demonstrated that cisplatin down-regulates the expression of the taurine transporter gene (Ta...

    Authors: Xiaobin Han and Russell W Chesney

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S28

    Content type: Review

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  29. Perinatal taurine exposure has long-term effects on the arterial pressure and renal function. This study tests its influence on renal potassium excretion in young adult, conscious rats. Female Sprague-Dawley r...

    Authors: Sanya Roysommuti, Pisamai Malila, Wichaporn Lerdweeraphon, Dusit Jirakulsomchok and J Michael Wyss

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S29

    Content type: Review

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  30. Perinatal taurine depletion leads to several physiological impairments in adult life, in part, due to taurine’s effects on the renin-angiotensin system, a crucial regulator of growth and differentiation during...

    Authors: Atcharaporn Thaeomor, J Michael Wyss, Dusit Jirakulsomchok and Sanya Roysommuti

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S30

    Content type: Review

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  31. Perinatal taurine exposure influences renal function in adult female offspring. This study tests the hypothesis that prenatal rather than postnatal taurine exposure alters renal function in adult conscious mal...

    Authors: Sanya Roysommuti, Pisamai Malila, Dusit Jirakulsomchok and J Michael Wyss

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S31

    Content type: Review

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  32. Taurine possesses membrane stabilization, osmoregulatory and antioxidant properties, aspects of relevance to ischemic injury. We tested the hypothesis that body taurine status is a determinant of renal ischemi...

    Authors: Mahmood S Mozaffari, Rafik Abdelsayed, Champa Patel, Hereward Wimborne, Jun Yao Liu and Stephen W Schaffer

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S32

    Content type: Review

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  33. Taurine plays an important role in reducing physiological stress. Recent studies indicated that taurine may serve as an anti-obesity agent at the cellular level. This study characterizes taurine’s potential an...

    Authors: Hye Min Kim, Chang-Hee Do and Dong Hee Lee

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S33

    Content type: Review

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  34. Prevalence of metabolic syndrome (MS) is rapidly increasing worldwide. To investigate the spread of MS risks and its relationship with eating habits including fish intake, we carried out a health examination f...

    Authors: Atsumi Hamada, Mari Mori, Hideki Mori, Alfa Muhihi, Marina Njelekela, Zablon Masesa, Jacob Mtabaji and Yukio Yamori

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S34

    Content type: Review

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  35. When used in overdoses, acetaminophen (APAP) is a common cause of morbidity and mortality in humans. At present, N-acetylcysteine (NAC) is the antidote of choice for acetaminophen overdoses. Prompt administrat...

    Authors: Miteshkumar Acharya and Cesar A Lau-Cam

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S35

    Content type: Review

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  37. In the present study, we investigated the changes of uptake and efflux transport of taurine under various stress conditions using rat conditionally immortalized syncytiotrophoblast cell line (TR-TBT cells), as in...

    Authors: Na-Young Lee and Young-Sook Kang

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S37

    Content type: Review

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  38. Low birth weight is associated with an increased risk of developing impaired glucose tolerance, and eventually type 2 diabetes in adult life. Gestational protein restriction in rodents gives rise to a low birt...

    Authors: Ole Hartvig Mortensen, Hanne Lodberg Olsen, Lis Frandsen, Peter Eigil Nielsen, Finn Cilius Nielsen, Niels Grunnet and Bjørn Quistorff

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S38

    Content type: Review

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  39. Nelumbo nucifera, known as sacred lotus, is a well-known medicinal plant and this lotus root is commonly used as food compared to different parts of this plant. This study was conducted to investigate the antioxi...

    Authors: Huan Du, Xu Zhao, Jeong-Soon You, Ji-Yeon Park, Sung-Hoon Kim and Kyung-Ja Chang

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S39

    Content type: Research

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  40. The purpose of this study was to investigate the dietary taurine intake, nutrients intake, dietary habits and life stress by depression in Korean female college students.

    Authors: Ji-Yeon Park, Jeong-Soon You and Kyung-Ja Chang

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S40

    Content type: Research

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  41. Constipation is a common gastrointestinal symptom in Korea as well as in Western countries. This study was performed to investigate the dietary taurine intake, nutrient status, and life stress of functional co...

    Authors: Jeong-Soon You, Ji-Yeon Park and Kyung-Ja Chang

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S41

    Content type: Research

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  42. Lotus (Nelumbo nucifera) leaf has been used to treat obesity. The purpose of this study was to investigate the antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in...

    Authors: Huan Du, Jeong-Soon You, Xu Zhao, Ji-Yeon Park, Sung-Hoon Kim and Kyung-Ja Chang

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S42

    Content type: Research

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  43. Since our previous report on WHO CARDIAC Study data demonstrated that 24-hour urinary (24U) taurine (Tau) excretion was a useful biomarker of seafood (SF) intake and inversely related to the mortality rates of...

    Authors: Mari Mori, Hideki Mori, Atsumi Hamada and Yukio Yamori

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S43

    Content type: Review

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  44. Calculus Bovis (:C.Bovis) is one of the most precious and commonly-used medicinal materials in Japan and China. As the natural occurrence is very rare, a source of supply for C. Bovis is far behind the actual nee...

    Authors: Kyoko Takahashi, Yuko Azuma, Kayoko Shimada, Tadashi Saito, Masaya Kawase and Stephen W Schaffer

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S44

    Content type: Review

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  46. It has been verified that taurine has some preventive effects on diabetes and its complications when used alone or together with other drugs, but there are few reports about taurine on the prevention of diabet...

    Authors: Shumei Lin, Jiancheng Yang, Gaofeng Wu, Mei Liu, Xinhong Luan, Qiufeng Lv, He Zhao and Jianmin Hu

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S46

    Content type: Review

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  47. The prevalence of metabolic syndrome (MS) in children and adolescents has been increasing at an alarming rate. MS risks during childhood and adolescence adversely affect health conditions in later life. Thus, ...

    Authors: Megumi Ishikawa, Shiho Arai, Mio Takano, Atsumi Hamada, Kazuhiro Kunimasa and Mari Mori

    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S47

    Content type: Review

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