Journal of Biomedical Science is supported by the National Science and Technology Council (NSTC), Taiwan.
Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS
In the central nervous system regions of the sporadic and familial FTLD and ALS patients, TDP-43 has been identified as the major component of UBIs inclusions which is abnormally hyperphosphorylated, ubiquitin...