Journal of Biomedical Science is supported by the National Science and Technology Council (NSTC), Taiwan.
Sodium valproate-induced congenital cardiac abnormalities in mice are associated with the inhibition of histone deacetylase
Valproic acid, a widely used anticonvulsant drug, is a potent teratogen resulting in various congenital abnormalities. However, the mechanisms underlying valproic acid induced teratogenesis are nor clear. Rece...