Journal of Biomedical Science is supported by the National Science and Technology Council (NSTC), Taiwan.
Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity
Sodium/iodide symporter (NIS) mediates the active transport and accumulation of iodide from the blood into the thyroid gland. His-226 located in the extracellular region of NIS has been demonstrated to be crit...