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792 result(s) for 'cancer' within Journal of Biomedical Science

Page 3 of 16

  1. Human Papillomavirus type 16 (HPV16) has been associated with a subset of head and neck cancers. Two HPV encoded oncogenic proteins, E6 ... important for the malignant progression of HPV-associated cancers. A spo...

    Authors: Ssu-Hsueh Tseng, Li Liu, Shiwen Peng, Jinhwi Kim, Louise Ferrall, Chien-Fu Hung and T. -C. Wu
    Citation: Journal of Biomedical Science 2021 28:63
    Content type: Research Published on:

  2. Damage-associated molecular patterns (DAMPs) are associated with immunogenic cell death and have the ability to enhance maturation and antigen presentation of dendritic cells (DCs). Specific microtubule-depolymer...

    Authors: Chih-Chun Wen, Hui-Ming Chen, Swey-Shen Chen, Li-Ting Huang, Wei-Ting Chang, Wen-Chi Wei, Li-Chen Chou, Palanisamy Arulselvan, Jin-Bin Wu, Sheng-Chu Kuo and Ning-Sun Yang
    Citation: Journal of Biomedical Science 2011 18:44
    Content type: Research Published on:

  3. As of 2020, hepatocellular carcinoma (HCC), a form of liver cancer, stood as the third most prominent contributor to global cancer-related mortality. Combining immune checkpoint inhibitors (...+ T cells and creat...

    Authors: Da-Liang Ou, Zi-Xian Liao, Ivan M. Kempson, Lin Li, Pan-Chyr Yang and S.-Ja Tseng
    Citation: Journal of Biomedical Science 2024 31:1
    Content type: Research Published on:

  4. Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine receptor 4 (CXCR4) is involved in the carcinogenesis of human gastric cancer, where it stimulates angiogenesis and favors metastasis ....

    Authors: Yung-Yu Hsieh, Chien-Heng Shen, Wen-Shih Huang, Chih-Chien Chin, Yi-Hung Kuo, Meng Chiao Hsieh, Hong-Ren Yu, Te-Sheng Chang, Tseng-Hsi Lin, Yung-Wei Chiu, Cheng-Nan Chen, Hsing-Chun Kuo and Shui-Yi Tung
    Citation: Journal of Biomedical Science 2014 21:59
    Content type: Research Published on:

  5. Cancer is an international health problem, and the ... (RRM-MV) as a candidate for skin cancer therapy. RRM-MV was designed using the ... and its effect was examined on human skin cancer and normal human skin cel...

    Authors: Nahlah M Almansour, Elena Pirogova, Peter J Coloe, Irena Cosic and Taghrid S Istivan
    Citation: Journal of Biomedical Science 2012 19:65
    Content type: Research Published on:

  6. Precision medicine is becoming the standard of care in anti-cancer treatment. The personalized precision management of cancer patients highly relies on the improvement of...

    Authors: Wen-Chi Yang, Feng-Ming Hsu and Pan-Chyr Yang
    Citation: Journal of Biomedical Science 2020 27:82
    Content type: Review Published on:

  9. E26 transformation-specific (ETS) transcription variant 5 (ETV5), also known as ETS-related molecule (ERM), exerts versatile functions in normal physiological processes, including branching morphogenesis, neural ...

    Authors: Yi Wei, Shenqi Han, Jingyuan Wen, Jingyu Liao, Junnan Liang, Jingjing Yu, Xiaoping Chen, Shuai Xiang, Zhao Huang and Bixiang Zhang
    Citation: Journal of Biomedical Science 2023 30:17
    Content type: Review Published on:

  10. Multiple databases of lung cancer patients were integratively analyzed to screen Rab...Rab37 knockout mice and specimens of lung cancer patients were used to validate the concept.

    Authors: Wan-Ting Kuo, I-Ying Kuo, Hung-Chia Hsieh, Ssu-Ting Wu, Wu-Chou Su and Yi-Ching Wang
    Citation: Journal of Biomedical Science 2024 31:20
    Content type: Research Published on:

  12. Human olfactomedin 4 (OLFM4) gene is a secreted glycoprotein more commonly known as the anti-apoptotic molecule GW112. OLFM4 is found to be frequently up-regulated in many types of human tumors including gastric

    Authors: Rui-hua Liu, Mei-hua Yang, Hua Xiang, Li-ming Bao, Hua-an Yang, Li-wen Yue, Xue Jiang, Na Ang, Li-ya Wu and Yi Huang
    Citation: Journal of Biomedical Science 2012 19:38
    Content type: Research Published on:

  13. Shikonin, a phytochemical purified from Lithospermum erythrorhizon..., has been shown to confer diverse pharmacological activities, including accelerating granuloma formation, wound healing, anti-inflammation and...

    Authors: Hui-Ming Chen, Pi-Hsueh Wang, Kandan Aravindaram, Yun-Hsiang Chen, Hsiu-Hui Yu, Wen-Chin Yang and Ning-Sun Yang
    Citation: Journal of Biomedical Science 2012 19:42
    Content type: Research Published on:

  14. The tumor microenvironment is characterized by inflammation-like and immunosuppression situations. Although cancer-associated fibroblasts (CAFs) are among the major stromal cell types in various solid cancers, in...

    Authors: Feng-Wei Chen, Yung-Ling Wu, Chao-Chun Cheng, Yu-Wei Hsiao, Jhih-Ying Chi, Liang-Yi Hung, Chih-Peng Chang, Ming-Derg Lai and Ju-Ming Wang
    Citation: Journal of Biomedical Science 2024 31:10
    Content type: Research Published on:

  15. NKX3.1, a prostate-specific tumor suppressor, is either genomically lost or its protein levels are severely downregulated, which are invariably associated with poor prognosis in prostate cancer (PCa). Nevertheles...

    Authors: Moloud Aflaki Sooreshjani, Mohini Kamra, Amina Zoubeidi and Kavita Shah
    Citation: Journal of Biomedical Science 2021 28:68
    Content type: Research Published on:

  17. MAP4K3 (also named GLK) is a serine/threonine kinase, which belongs to the mammalian Ste20-like kinase family. At 22 years of age, GLK was initially cloned and identified as an upstream activator of the MAPK JNK ...

    Authors: Huai-Chia Chuang and Tse-Hua Tan
    Citation: Journal of Biomedical Science 2019 26:82
    Content type: Review Published on:

  19. Heme oxygenase-1 (HO-1) is a rate-limiting enzyme catalyzing oxidative degradation of cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in mammalian cells. In addition to its primary role i...

    Authors: Lee-Young Chau
    Citation: Journal of Biomedical Science 2015 22:22
    Content type: Review Published on:

  20. Heteronemin (Haimian jing) is a sesterterpenoid-type natural marine product that is isolated from sponges and has anticancer properties. It inhibits cancer cell proliferation via different mechanisms, such as ......

    Authors: Kuan Wang, Yi-Fong Chen, Yu-Chen S. H. Yang, Haw-Ming Huang, Sheng-Yang Lee, Ya-Jung Shih, Zi-Lin Li, Jacqueline Whang-Peng, Hung-Yun Lin and Paul J. Davis
    Citation: Journal of Biomedical Science 2022 29:41
    Content type: Review Published on:

  21. Mounting evidences have showed the important role of transforming growth factor-β (TGF-β) in immunological surveillance of tumors. Some studies have also indicated human leukocyte antigen (HLA)-G-associated immun...

    Authors: Zhongzheng Guan, Bingtan Song, Fengjun Liu, Dong Sun, Kexin Wang and Hui Qu
    Citation: Journal of Biomedical Science 2015 22:107
    Content type: Research Published on:

  22. H. pylori CagL-Y58/E59 increase gastric cancer risk by stronger binding with integrin to...H. pylori can secrete high temperature requirement A (HtrA) to mediate E-Cadherin cleavage for gastric epithelial junctio...

    Authors: Yi-Chun Yeh, Hsin-Yu Kuo, Wei-Lun Chang, Hsiao-Bai Yang, Cheng-Chan Lu, Hsiu-Chi Cheng, Ming-Shiang Wu and Bor-Shyang Sheu
    Citation: Journal of Biomedical Science 2019 26:4
    Content type: Research Published on:

  23. PTEN is a tumor suppressor gene which is involved in cellular proliferation, differentiation, and apoptosis. Loss or down-regulation of PTEN plays an important role in human cancers development. In this study, we...

    Authors: Yaghoub Yazdani, Touraj Farazmandfar, Hossein Azadeh and Zeinab Zekavatian
    Citation: Journal of Biomedical Science 2016 23:9
    Content type: Research Published on:

  24. Numerous studies have shown that Id-1 (Inhibitor of differentiation 1) is upregulated in several cancers and associated with tumor malignant characters. However ... of Id-1 in non-small cell lung cancer (NSCLC) r...

    Authors: Jie Li, Yingjie Li, Bin Wang, Yongfu Ma and Ping Chen
    Citation: Journal of Biomedical Science 2017 24:95
    Content type: Research Published on:

  25. In normal and neoplastic cells, growth-promoting, proangiogenic, cytotoxic and pro-apoptotic effects have all been attributed to cathelicidin antimicrobial peptide (CAMP...). Nevertheless, little is known about t...

    Authors: Janice García-Quiroz, Rocío García-Becerra, Nancy Santos-Martínez, Euclides Avila, Fernando Larrea and Lorenza Díaz
    Citation: Journal of Biomedical Science 2016 23:78
    Content type: Research Published on:

  26. We determined the changes in adipogenic, osteogenic differentiation, phenotypic and gene expression in MSC during treatment with chemotherapeutic drugs cytarabine, daunorubicin and vincristine. We also tested ant...

    Authors: Chinnapaka Somaiah, Atul Kumar, Renu Sharma, Amit Sharma, Trishna Anand, Jina Bhattacharyya, Damodar Das, Sewali Deka Talukdar and Bithiah Grace Jaganathan
    Citation: Journal of Biomedical Science 2018 25:5
    Content type: Research Published on:

  28. Luteinizing hormone-releasing hormone (LH-RH) agonists are the standard for androgen deprivation therapy (ADT) in prostate cancer (PCa) patients. Current guidelines recommend serum...

    Authors: Juan Morote, Imma Comas, Roser Ferrer, Jacques Planas, Anna Celma and Lucas Regis
    Citation: Journal of Biomedical Science 2017 24:81
    Content type: Research Published on:

  29. Immune checkpoints or coinhibitory receptors, such as cytotoxic T lymphocyte antigen (CTLA)-4 and programmed death (PD)-1, play important roles in regulating T cell responses, and they were proven to be effective...

    Authors: Hwei-Fang Tsai and Ping-Ning Hsu
    Citation: Journal of Biomedical Science 2017 24:35
    Content type: Review Published on:

  30. All cells in the changing tumor microenvironment (TME) need a class of checkpoints to regulate the balance among exocytosis, endocytosis, recycling and degradation. The vesicular trafficking and secretion pathway...

    Authors: I.-Ying Kuo, Chih-Hsiung Hsieh, Wan-Ting Kuo, Chih-Peng Chang and Yi-Ching Wang
    Citation: Journal of Biomedical Science 2022 29:56
    Content type: Review Published on:

  31. CRISPR (clustered regularly interspaced short palindromic repeats) systems are one of the most fascinating tools of the current era in molecular biotechnology. With the ease that they provide in genome editing, C...

    Authors: Guzide Bender, Rezan Fahrioglu Yamaci and Bahar Taneri
    Citation: Journal of Biomedical Science 2021 28:77
    Content type: Review Published on:

  32. Chromatin remodeling is an essential cellular process for organizing chromatin structure into either open or close configuration at specific chromatin locations by orchestrating and modifying histone complexes. T...

    Authors: Jayaprakash Mandal, Prativa Mandal, Tian-Li Wang and Ie-Ming Shih
    Citation: Journal of Biomedical Science 2022 29:71
    Content type: Review Published on:

  33. Recent advancements in cancer biology field suggest that glucose metabolism is a potential target for cancer treatment. However, little if anything is known about the metabolic profile of cancer stem cells (CSCs)...

    Authors: Han-Shui Hsu, Chen-Chi Liu, Jiun-Han Lin, Tien-Wei Hsu, Jyuan-Wei Hsu, Anna Fen-Yau Li and Shih-Chieh Hung
    Citation: Journal of Biomedical Science 2020 27:5
    Content type: Research Published on:

  35. Obesity and its comorbidities constitute a serious health burden worldwide. Leptin plays an important role in diet control; however, it has a stimulatory potential on cancer cell proliferation. The OB3 peptide, a...

    Authors: Yu-Tang Chin, Le-Ming Wang, Meng-Ti Hsieh, Ya-Jung Shih, André Wendindondé Nana, Chun A. Changou, Yu-Chen S. H. Yang, Hsien-Chung Chiu, Earl Fu, Paul J. Davis, Heng-Yuan Tang and Hung-Yun Lin
    Citation: Journal of Biomedical Science 2017 24:51
    Content type: Research Published on:

  37. Lung cancer is the most common cause of cancer-related death worldwide, less than 7% ... years following diagnosis across all stages of lung cancer. Late stage of diagnosis and lack of ... better understanding of...

    Authors: Chantal Hoi Yin Cheung and Hsueh-Fen Juan
    Citation: Journal of Biomedical Science 2017 24:37
    Content type: Review Published on:

  38. Despite the recent progress in screening and therapy, a majority of prostate cancer cases eventually attain hormone refractory and chemo- ... doses for only palliative management of these prostate cancers. Theref...

    Authors: Rishi Kumar Gara, Vikas Kumar Srivastava, Shivali Duggal, Jaspreet Kaur Bagga, MLB Bhatt, Sabyasachi Sanyal and Durga Prasad Mishra
    Citation: Journal of Biomedical Science 2015 22:26
    Content type: Research Published on:

  39. Cancer stem cells are capable of undergoing cell division after surviving cancer therapies, leading to tumor progression and recurrence. Inhibitory agents against cancer stem cells may be therapeutically used for...

    Authors: Chun-Chia Cheng, Po-Nien Liao, Ai-Sheng Ho, Ken-Hong Lim, Jungshan Chang, Ying-Wen Su, Caleb Gon-Shen Chen, Ya-Wen Chiang, Bi-Ling Yang, Huan-Chau Lin, Yu-Cheng Chang, Chun-Chao Chang and Yi-Fang Chang
    Citation: Journal of Biomedical Science 2018 25:60
    Content type: Research Published on:

  40. Zinc finger proteins are the largest transcription factor family in human genome. The diverse combinations and functions of zinc finger motifs make zinc finger proteins versatile in biological processes, includin...

    Authors: Jayu Jen and Yi-Ching Wang
    Citation: Journal of Biomedical Science 2016 23:53
    Content type: Review Published on:

  41. Chronic stress results in disturbances of body hormones through the neuroendocrine system. Cancer patients often experience recurrent anxiety and restlessness ... suggest that chronic stress affects the outcome o...

    Authors: Jiajing Yan, Yibing Chen, Minhua Luo, Xinyu Hu, Hongsheng Li, Quentin Liu and Zhengzhi Zou
    Citation: Journal of Biomedical Science 2023 30:8
    Content type: Review Published on:

  42. During metastasis, cancer cells require anokis resistant mechanism to survive ... tissues. As anoikis sensitization may benefit for cancer therapy, this study demonstrated the potential of ... (Avicenniaceae) to ...

    Authors: Arisara Prateep, Somruethai Sumkhemthong, Wiranpat Karnsomwan, Wanchai De-Eknamkul, Supakarn Chamni, Pithi Chanvorachote and Chatchai Chaotham
    Citation: Journal of Biomedical Science 2018 25:32
    Content type: Research Published on:

  43. Breast cancer is the most common malignancy in women and a public health problem worldwide. Breast cancer is often accompanied by an inflammatory process ... and its implication in different phenotypes of breast

    Authors: Isela Martínez-Reza, Lorenza Díaz and Rocío García-Becerra
    Citation: Journal of Biomedical Science 2017 24:90
    Content type: Review Published on:

  44. MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that have been found highly conserved among species. MiRNAs are able to negatively regulate gene expression through base pairing of 3’ UTRs of th...

    Authors: Shih-Hsuan Chan and Lu-Hai Wang
    Citation: Journal of Biomedical Science 2015 22:9
    Content type: Review Published on:

  45. Cancer stem cells (CSCs) are subpopulations of cancer cells sharing similar characteristics as normal stem ... drive tumour growth and heterogeneity. Throughout the cancer progression, CSC can further be induced ...

    Authors: Ain Zubaidah Ayob and Thamil Selvee Ramasamy
    Citation: Journal of Biomedical Science 2018 25:20
    Content type: Review Published on:

  46. Immunotherapy has recently emerged as the fourth pillar of cancer treatment, joining surgery, radiation, and chemotherapy ... immune-checkpoint inhibitors have opened new avenues in cancer immunology. However, th...

    Authors: Yoshiko Iwai, Junzo Hamanishi, Kenji Chamoto and Tasuku Honjo
    Citation: Journal of Biomedical Science 2017 24:26
    Content type: Review Published on:

  47. Cancer along with cardiovascular disease are the main ... the industrialised countries around the World. Conventional cancer treatments are losing their therapeutic uses due ... a novel approach to treat many dis...

    Authors: Susan Marqus, Elena Pirogova and Terrence J. Piva
    Citation: Journal of Biomedical Science 2017 24:21
    Content type: Review Published on:

  48. Limitless self-renewal is one of the hallmarks of cancer and is attained by telomere maintenance, essentially...TERT) activation. Transcriptional regulation of hTERT...is believed to play a major role in telomera...

    Authors: Ricardo Leão, Joana Dias Apolónio, Donghyun Lee, Arnaldo Figueiredo, Uri Tabori and Pedro Castelo-Branco
    Citation: Journal of Biomedical Science 2018 25:22
    Content type: Review Published on:

  49. Increasing evidence suggests that transforming growth factor-beta 1 (TGF-β1) triggers epithelial to mesenchymal transition (EMT) and facilitates breast cancer stem cell differentiation. Gelsolin (GSN) is ... TGF-...

    Authors: Zhi-Yuan Chen, Pei-Wen Wang, Dar-Bin Shieh, Kuan-Ying Chiu and Ying-Ming Liou
    Citation: Journal of Biomedical Science 2015 22:90
    Content type: Research Published on:

  50. Thyroid hormone analogues—particularly, l-thyroxine (T4...) has been shown to be relevant to the functions of a variety of cancers. Integrin αvβ3 is a plasma membrane structural ... to signal transduction pathway...

    Authors: Yu-Chen S. H. Yang, Po-Jui Ko, Yi-Shin Pan, Hung-Yun Lin, Jacqueline Whang-Peng, Paul J. Davis and Kuan Wang
    Citation: Journal of Biomedical Science 2021 28:24
    Content type: Review Published on:
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Journal of Biomedical Science

ISSN: 1423-0127