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827 result(s) for 'review' within Journal of Biomedical Science

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  1. Living organisms are continuously exposed to multiple internal and external stimuli which may influence their emotional, psychological, and physical behaviors. Stress can modify brain structures, reduces function...

    Authors: Ola Salhab, Luna Khayat and Nada Alaaeddine
    Citation: Journal of Biomedical Science 2022 29:77
  2. Dengue virus infection presents a wide spectrum of manifestations including asymptomatic condition, dengue fever (DF), or severe forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) in af...

    Authors: Daisy Vanitha John, Yee-Shin Lin and Guey Chuen Perng
    Citation: Journal of Biomedical Science 2015 22:83
  3. Human corneal endothelial cells are notorious for their restricted proliferative ability in vivo and in vitro. Hence, injury or dysfunction of these cells may easily result in blindness. Currently, the only treat...

    Authors: Shuangling Chen, Qin Zhu, Hong Sun, Yuan Zhang, Sean Tighe, Li Xu and Yingting Zhu
    Citation: Journal of Biomedical Science 2019 26:2
  4. Parkinson’s disease (PD) is the most common movement disorder and manifests as resting tremor, rigidity, bradykinesia, and postural instability. Pathologically, PD is characterized by selective loss of dopamin...

    Authors: Meng-Ling Chen and Ruey-Meei Wu
    Citation: Journal of Biomedical Science 2018 25:52
  5. Human mesenchymal stem cells (MSCs) are multilineage somatic progenitor/stem cells that have been shown to possess immunomodulatory properties in recent years. Initially met with much skepticism, MSC immunomodula...

    Authors: Li-Tzu Wang, Chiao-Hsuan Ting, Men-Luh Yen, Ko-Jiunn Liu, Huey-Kang Sytwu, Kenneth K. Wu and B. Linju Yen
    Citation: Journal of Biomedical Science 2016 23:76
  6. The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a growing area in cell biology. Increasing evidence has revealed canonical and noncanonical functions of long and small ncRNAs...

    Authors: Ming-Che Kuo, Sam Chi-Hao Liu, Ya-Fang Hsu and Ruey-Meei Wu
    Citation: Journal of Biomedical Science 2021 28:78
  7. Hypoxia is an important microenvironmental factor that induces cancer metastasis. Hypoxia/hypoxia-inducible factor-1α (HIF-1α) regulates many important steps of the metastatic processes, especially epithelial-mes...

    Authors: Ya-Ping Tsai and Kou-Juey Wu
    Citation: Journal of Biomedical Science 2012 19:102
  8. The global burden of invasive fungal infections (IFIs) has shown an upsurge in recent years due to the higher load of immunocompromised patients suffering from various diseases. The role of early and accurate dia...

    Authors: Wenjie Fang, Junqi Wu, Mingrong Cheng, Xinlin Zhu, Mingwei Du, Chang Chen, Wanqing Liao, Kangkang Zhi and Weihua Pan
    Citation: Journal of Biomedical Science 2023 30:42
  9. Bipolar disorder is a decidedly heterogeneous and multifactorial disease, with a high individual and societal burden. While not all patients display overt markers of elevated inflammation, significant evidence su...

    Authors: Gregory H. Jones, Courtney M. Vecera, Omar F. Pinjari and Rodrigo Machado-Vieira
    Citation: Journal of Biomedical Science 2021 28:45
  10. The Ras homolog gene family member A (RhoA) is the founding member of Rho GTPase superfamily originally studied in cancer cells where it was found to stimulate cell cycle progression and migration. RhoA acts as a...

    Authors: Lucia Sophie Kilian, Jakob Voran, Derk Frank and Ashraf Yusuf Rangrez
    Citation: Journal of Biomedical Science 2021 28:33
  11. Sepsis represents a critical medical condition stemming from an imbalanced host immune response to infections, which is linked to a significant burden of disease. Despite substantial efforts in laboratory and cli...

    Authors: Mohammed A. Gafar, Calvin A. Omolo, Eman Elhassan, Usri H. Ibrahim and Thirumala Govender
    Citation: Journal of Biomedical Science 2024 31:40
  12. Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a clinically critical pathogen that causes severe infection. Due to improper antibiotic administration, the prevalence of CRKP infection has been increasing co...

    Authors: Yu-Ming Zhang, Mei-Fen Tsao, Ching-Yu Chang, Kuan-Ting Lin, Joseph Jordan Keller and Hsiu-Chen Lin
    Citation: Journal of Biomedical Science 2023 30:25
  13. Neurological disorders such as stroke, multiple sclerosis, as well as the neurodegenerative diseases Parkinson's or Alzheimer's disease are accompanied or even powered by danger associated molecular patterns (DAM...

    Authors: Reiner Kunze, Silvia Fischer, Hugo H. Marti and Klaus T. Preissner
    Citation: Journal of Biomedical Science 2023 30:64
  14. Pregnancy associated plasma protein-A (PAPP-A) plays an integral role in breast cancer (BC), especially triple negative breast cancer (TNBC). This subtype accounts for the most aggressive BC, possesses high tumor...

    Authors: Arpita Poddar, Farah Ahmady, Sushma R. Rao, Revati Sharma, George Kannourakis, Prashanth Prithviraj and Aparna Jayachandran
    Citation: Journal of Biomedical Science 2024 31:23
  15. Breast cancer is the most common solid cancer that affects female population globally. MicroRNAs (miRNAs) are short non-coding RNAs that can regulate post-transcriptional modification of multiple downstream genes...

    Authors: Zhi Xiong Chong, Swee Keong Yeap and Wan Yong Ho
    Citation: Journal of Biomedical Science 2021 28:21
  16. Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral functions during a viral invasion. However, co-evolution and co-adaptation between viruses and autophagy have armed viruse...

    Authors: Tong Chen, Shaoyu Tu, Ling Ding, Meilin Jin, Huanchun Chen and Hongbo Zhou
    Citation: Journal of Biomedical Science 2023 30:5
  17. Effective and validated animal models are valuable to investigate the pathogenesis and potential therapeutics for human diseases. There is much concern for diabetic retinopathy (DR) in that it affects substantial...

    Authors: Dong Hyun Jo, Chang Sik Cho, Jin Hyoung Kim, Hyoung Oh Jun and Jeong Hun Kim
    Citation: Journal of Biomedical Science 2013 20:38
  18. Although rheumatoid arthritis affects 1% of the global population, the role of rheumatoid cachexia, which occurs in up to a third of patients, is relatively neglected as research focus, despite its significant co...

    Authors: T. Ollewagen, K. H. Myburgh, M. van de Vyver and C. Smith
    Citation: Journal of Biomedical Science 2021 28:15
  19. Heteronemin (Haimian jing) is a sesterterpenoid-type natural marine product that is isolated from sponges and has anticancer properties. It inhibits cancer cell proliferation via different mechanisms, such as ...

    Authors: Kuan Wang, Yi-Fong Chen, Yu-Chen S. H. Yang, Haw-Ming Huang, Sheng-Yang Lee, Ya-Jung Shih, Zi-Lin Li, Jacqueline Whang-Peng, Hung-Yun Lin and Paul J. Davis
    Citation: Journal of Biomedical Science 2022 29:41
  20. Obesity is nowadays considered a pandemic which prevalence’s has been steadily increasingly in western countries. It is a dynamic, complex, and multifactorial disease which propitiates the development of several ...

    Authors: José Antônio Fagundes Assumpção, Gabriel Pasquarelli-do-Nascimento, Mariana Saldanha Viegas Duarte, Martín Hernan Bonamino and Kelly Grace Magalhães
    Citation: Journal of Biomedical Science 2022 29:12
  21. CRISPR (clustered regularly interspaced short palindromic repeats) systems are one of the most fascinating tools of the current era in molecular biotechnology. With the ease that they provide in genome editing, C...

    Authors: Guzide Bender, Rezan Fahrioglu Yamaci and Bahar Taneri
    Citation: Journal of Biomedical Science 2021 28:77
  22. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the most challenging pandemic in this century. Conside...

    Authors: Yen-Der Li, Wei-Yu Chi, Jun-Han Su, Louise Ferrall, Chien-Fu Hung and T.-C. Wu
    Citation: Journal of Biomedical Science 2020 27:104
  23. The secreted glycoprotein leucine-rich α-2 glycoprotein 1 (LRG1) was first described as a key player in pathogenic ocular neovascularization almost a decade ago. Since then, an increasing number of publications h...

    Authors: Carlotta Camilli, Alexandra E. Hoeh, Giulia De Rossi, Stephen E. Moss and John Greenwood
    Citation: Journal of Biomedical Science 2022 29:6
  24. Intercellular signaling by cytokines is a vital feature of the innate immune system. In skin, an inflammatory response is mediated by cytokines and an entwined network of cellular communication between T-cells an...

    Authors: Rasmus O Bak and Jacob G Mikkelsen
    Citation: Journal of Biomedical Science 2010 17:53
  25. DNA transposons are primitive genetic elements which have colonized living organisms from plants to bacteria and mammals. Through evolution such parasitic elements have shaped their host genomes by replicating...

    Authors: Kristian Alsbjerg Skipper, Peter Refsing Andersen, Nynne Sharma and Jacob Giehm Mikkelsen
    Citation: Journal of Biomedical Science 2013 20:92
  26. Therapeutic antibodies are instrumental in improving the treatment outcome for certain disease conditions. However, to enhance their efficacy and specificity, many efforts are continuously made. One of the approa...

    Authors: Tomasz Klaus and Sameer Deshmukh
    Citation: Journal of Biomedical Science 2021 28:11
  27. In modern societies, with an increase in the older population, age-related neurodegenerative diseases have progressively become greater socioeconomic burdens. To date, despite the tremendous effort devoted to ...

    Authors: Ching-Pang Chang, Kuo-Chen Wu, Chien-Yu Lin and Yijuang Chern
    Citation: Journal of Biomedical Science 2021 28:70
  28. After publication of our article, it was noted that we inadvertently failed to include the complete list of authors. The full list, including co-authors, has now been added and the Authors' contributions and C...

    Authors: Sang Soo Hah, Paul T Henderson and Kenneth W Turteltaub
    Citation: Journal of Biomedical Science 2009 16:111

    The original article was published in Journal of Biomedical Science 2009 16:54

  29. The neuronal ceroid lipofuscinoses (NCLs), commonly known as Batten disease, belong to a family of neurological disorders that cause blindness, seizures, loss of motor function and cognitive ability, and prema...

    Authors: Robert J. Huber
    Citation: Journal of Biomedical Science 2020 27:64

    The Correction to this article has been published in Journal of Biomedical Science 2020 27:94

  30. Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease whose etiology remains largely unknown. The uncontrolled oxidative stress in SLE contributes to functional oxidative modifications of cellu...

    Authors: Dilip Shah, Nidhi Mahajan, Sangita Sah, Swapan K Nath and Bishnuhari Paudyal
    Citation: Journal of Biomedical Science 2014 21:23
  31. PCD is crucial for efficient and careful clearance of excessive, depleted, or obsolete ovarian structures for ovarian cycling. Moreover, PCD facilitates selection of high-quality oocytes and formation of the ovar...

    Authors: Mikhail S. Chesnokov, Aygun R. Mamedova, Boris Zhivotovsky and Gelina S. Kopeina
    Citation: Journal of Biomedical Science 2024 31:31
  32. Coronavirus Disease 2019 (COVID-19) has been the most severe public health challenge in this century. Two years after its emergence, the rapid development and deployment of effective COVID-19 vaccines have succes...

    Authors: Wei-Yu Chi, Yen-Der Li, Hsin-Che Huang, Timothy En Haw Chan, Sih-Yao Chow, Jun-Han Su, Louise Ferrall, Chien-Fu Hung and T.-C. Wu
    Citation: Journal of Biomedical Science 2022 29:82
  33. The global pandemic of COVID-19 has caused huge causality and unquantifiable loss of social wealth. The innate immune response is the first line of defense against SARS-CoV-2 infection. However, strong inflammato...

    Authors: Yiran Wang, Mandi Wu, Yichen Li, Ho Him Yuen and Ming-Liang He
    Citation: Journal of Biomedical Science 2022 29:27
  34. Unprecedented efforts of the researchers have been witnessed in the recent past towards the development of vaccine platforms for the control of the COVID-19 pandemic. Albeit, vaccination stands as a practical str...

    Authors: Kunal Nepali, Ram Sharma, Sachin Sharma, Amandeep Thakur and Jing-Ping Liou
    Citation: Journal of Biomedical Science 2022 29:65

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