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835 result(s) for 'review' within Journal of Biomedical Science

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  1. The global pandemic of COVID-19 has caused huge causality and unquantifiable loss of social wealth. The innate immune response is the first line of defense against SARS-CoV-2 infection. However, strong inflammato...

    Authors: Yiran Wang, Mandi Wu, Yichen Li, Ho Him Yuen and Ming-Liang He
    Citation: Journal of Biomedical Science 2022 29:27
    Content type: Review Published on:

  2. Unprecedented efforts of the researchers have been witnessed in the recent past towards the development of vaccine platforms for the control of the COVID-19 pandemic. Albeit, vaccination stands as a practical str...

    Authors: Kunal Nepali, Ram Sharma, Sachin Sharma, Amandeep Thakur and Jing-Ping Liou
    Citation: Journal of Biomedical Science 2022 29:65
    Content type: Review Published on:

  4. Taurine participates in a number of different physiologic and biologic processes in the kidney, often reflected by urinary excretion patterns. The kidney is key to aspects of taurine body pool size and homeostasi...

    Authors: Russell W Chesney, Xiaobin Han and Andrea B Patters
    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S4
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  5. Reactive oxygen species (ROS) are products of normal cellular metabolism and derive from various sources in different cellular compartments. Oxidative stress resultant from imbalance between ROS generation and an...

    Authors: Miroslava Majzunova, Ima Dovinova, Miroslav Barancik and Julie YH Chan
    Citation: Journal of Biomedical Science 2013 20:69
    Content type: Review Published on:

  6. Polycystic ovary syndrome (PCOS) is a state of altered steroid hormone production and activity. Chronic estrogen exposure or lack of progesterone due to ovarian dysfunction can result in endometrial hyperplasia a...

    Authors: Xin Li, Yi Feng, Jin-Fang Lin, HÃ¥kan Billig and Ruijin Shao
    Citation: Journal of Biomedical Science 2014 21:2
    Content type: Review Published on:

  7. Specific vulnerability and degeneration of the dopaminergic neurons in the substantia nigra pars compacta of the midbrain is the pathological hallmark of Parkinson’s disease. A number of transcription factors reg...

    Authors: Kambiz N Alavian, Sharmin Jeddi, Sahar I Naghipour, Pegah Nabili, Pawel Licznerski and Travis S Tierney
    Citation: Journal of Biomedical Science 2014 21:27
    Content type: Review Published on:

  8. Both Neurofibromatosis type I (NF1) and inclusion body myopathy with Paget's disease of bone and frontotemporal dementia (IBMPFD) are autosomal dominant genetic disorders. These two diseases are fully penetran...

    Authors: Yi-Ping Hsueh
    Citation: Journal of Biomedical Science 2012 19:33
    Content type: Review Published on:

  10. The coronavirus disease 2019 (COVID-19) pandemic has impacted human lifestyles around the world, causing huge distress in terms of public health systems, emergency response capacity and economic development. The ...

    Authors: Jaung-Geng Lin, Guan-Jhong Huang and Yi-Chang Su
    Citation: Journal of Biomedical Science 2023 30:30
    Content type: Review Published on:

  12. Cancer immunotherapy has revolutionized treatment and led to an unprecedented wave of immuno-oncology research during the past two decades. In 2018, two pioneer immunotherapy innovators, Tasuku Honjo and James...

    Authors: Austin W. T. Chiang, Hratch M. Baghdassarian, Benjamin P. Kellman, Bokan Bao, James T. Sorrentino, Chenguang Liang, Chih-Chung Kuo, Helen O. Masson and Nathan E. Lewis
    Citation: Journal of Biomedical Science 2021 28:50
    Content type: Review Published on:

  13. Cdk5 is a proline-directed serine/threonine protein kinase that governs a variety of cellular processes in neurons, the dysregulation of which compromises normal brain function. The mechanisms underlying the modu...

    Authors: Ping-Chieh Pao and Li-Huei Tsai
    Citation: Journal of Biomedical Science 2021 28:79
    Content type: Review Published on:

  14. Kaposi’s sarcoma-associated herpesvirus (KSHV), also designated human herpesvirus 8 (HHV-8), has been linked to Kaposi’s sarcoma, as well as to primary effusion lymphoma (PEL), and a subset of multicentric Cas...

    Authors: Mel Campbell and Yoshihiro Izumiya
    Citation: Journal of Biomedical Science 2020 27:41
    Content type: Review Published on:

  15. EVs, both from retinal and peripheral immune cells, increase complexity to BRB dysfunction in DR and AMD. Laden with bioactive cargoes, these EVs can modulate the retinal microenvironment, influencing disease pro...

    Authors: Beatriz Martins, Maria Pires, António Francisco Ambrósio, Henrique Girão and Rosa Fernandes
    Citation: Journal of Biomedical Science 2024 31:48
    Content type: Review Published on:

  16. Genome editing technologies hold great promise for numerous applications including the understanding of cellular and disease mechanisms and the development of gene and cellular therapies. Achieving high editing f...

    Authors: Nanna S. Mikkelsen and Rasmus O. Bak
    Citation: Journal of Biomedical Science 2023 30:51
    Content type: Review Published on:

  17. Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy because of their high immunomodulation ability, tropism towards inflamed and injured tissues, and their easy access and isolat...

    Authors: Wei-Zhan Zhuang, Yi-Heng Lin, Long-Jyun Su, Meng-Shiue Wu, Han-Yin Jeng, Huan-Cheng Chang, Yen-Hua Huang and Thai-Yen Ling
    Citation: Journal of Biomedical Science 2021 28:28
    Content type: Review Published on:

  19. Fibrosis can be defined as an excessive and deregulated deposition of extracellular matrix proteins, causing loss of physiological architecture and dysfunction of different tissues and organs. In the skin, fibros...

    Authors: Angelo Giuseppe Condorelli, May El Hachem, Giovanna Zambruno, Alexander Nystrom, Eleonora Candi and Daniele Castiglia
    Citation: Journal of Biomedical Science 2021 28:36
    Content type: Review Published on:

  20. Chromatin remodeling is an essential cellular process for organizing chromatin structure into either open or close configuration at specific chromatin locations by orchestrating and modifying histone complexes...

    Authors: Jayaprakash Mandal, Prativa Mandal, Tian-Li Wang and Ie-Ming Shih
    Citation: Journal of Biomedical Science 2022 29:71
    Content type: Review Published on:

  21. Despite the recent development of safe and highly effective direct-acting antivirals, hepatitis C virus (HCV) infection remains a significant health problem. In 2016, the World Health Organization set out to redu...

    Authors: Daniel Sepulveda-Crespo, Salvador Resino and Isidoro Martinez
    Citation: Journal of Biomedical Science 2020 27:78
    Content type: Review Published on:

  22. MDM2 has been established as a biomarker indicating poor prognosis for individuals undergoing immune checkpoint inhibitor (ICI) treatment for different malignancies by various pancancer studies. Specifically, ...

    Authors: Dantong Sun, Haili Qian, Junling Li and Puyuan Xing
    Citation: Journal of Biomedical Science 2024 31:17
    Content type: Review Published on:

  23. Antigen-specific immunotherapy using DNA vaccines has emerged as an attractive approach for the control of tumors. Another novel cancer therapy involves the employment of the vascular disrupting agent, 5,6-dim...

    Authors: Shiwen Peng, Archana Monie, Xiaowu Pang, Chien-Fu Hung and T-C Wu
    Citation: Journal of Biomedical Science 2011 18:21
    Content type: Research Published on:

  25. Effective vaccination against human papillomavirus (HPV) represents an opportunity to control cervical cancer. Peptide-based vaccines targeting HPV E6 and/or E7 antigens while safe, will most likely require ad...

    Authors: Chao-Yi Wu, Archana Monie, Xiaowu Pang, Chien-Fu Hung and T-C Wu
    Citation: Journal of Biomedical Science 2010 17:88
    Content type: Research Published on:

  26. All cells, including prokaryotes and eukaryotes, could release extracellular vesicles (EVs). EVs contain many cellular components, including RNA, and surface proteins, and are essential for maintaining normal int...

    Authors: Fusheng Zhang, Jinshuai Guo, Zhenghou Zhang, Meiqi Duan, Guang Wang, Yiping Qian, Haiying Zhao, Zhi Yang and Xiaofeng Jiang
    Citation: Journal of Biomedical Science 2022 29:14
    Content type: Review Published on:

  28. The molecular mechanisms that regulate embryogenesis and cardiac development are calibrated by multiple signal transduction pathways within or between different cell lineages via autocrine or paracrine mechanisms...

    Authors: Anushka Deshpande, Prithviraj Manohar Vijaya Shetty, Norbert Frey and Ashraf Yusuf Rangrez
    Citation: Journal of Biomedical Science 2022 29:38
    Content type: Review Published on:

  30. RNA has emerged as a revolutionary and important tool in the battle against emerging infectious diseases, with roles extending beyond its applications in vaccines, in which it is used in the response to the COVID...

    Authors: Hara Kang, Yun Ji Ga, Soo Hyun Kim, Young Hoon Cho, Jung Won Kim, Chaeyeon Kim and Jung-Yong Yeh
    Citation: Journal of Biomedical Science 2023 30:88
    Content type: Review Published on:

  31. Hemodynamic shear stress, the blood flow-generated frictional force acting on the vascular endothelial cells, is essential for endothelial homeostasis under normal physiological conditions. Mechanosensors on endo...

    Authors: Hsyue-Jen Hsieh, Ching-Ann Liu, Bin Huang, Anne HH Tseng and Danny Ling Wang
    Citation: Journal of Biomedical Science 2014 21:3
    Content type: Review Published on:

  33. Psychological stress is a global issue that affects at least one-third of the population worldwide and increases the risk of numerous psychiatric disorders. Accumulating evidence suggests that the gut and its inh...

    Authors: Tzu-Ting Lai, Chia-Wei Liou, Yu-Hsuan Tsai, Yuan-Yuan Lin and Wei-Li Wu
    Citation: Journal of Biomedical Science 2023 30:92
    Content type: Review Published on:

  34. A short open reading frame (sORFs) constitutes ≤ 300 bases, encoding a microprotein or sORF-encoded protein (SEP) which comprises ≤ 100 amino acids. Traditionally dismissed by genome annotation pipelines as meani...

    Authors: Alyssa Zi-Xin Leong, Pey Yee Lee, M. Aiman Mohtar, Saiful Effendi Syafruddin, Yuh-Fen Pung and Teck Yew Low
    Citation: Journal of Biomedical Science 2022 29:19
    Content type: Review Published on:

  36. Intracellular Ca2+ is one of the crucial signalings that modulate various cellular functions. The dysregulation of Ca2+ homeostasis has been suggested as an important event in driving the expression of the malign...

    Authors: Yih-Fung Chen, Ying-Ting Chen, Wen-Tai Chiu and Meng-Ru Shen
    Citation: Journal of Biomedical Science 2013 20:23
    Content type: Review Published on:

  37. Atherosclerosis is commonly appreciated to represent a chronic inflammatory response of the vascular wall, and its complications cause high mortality in patients. Angioplasty with stent replacement is commonly pe...

    Authors: Li-Jing Chen, Seh Hong Lim, Yi-Ting Yeh, Sheng-Chieh Lien and Jeng-Jiann Chiu
    Citation: Journal of Biomedical Science 2012 19:79
    Content type: Review Published on:

  38. Over the past few years, long non-coding RNAs (lncRNAs) are recognized as key regulators of gene expression at chromatin, transcriptional and posttranscriptional level with pivotal roles in various biological and...

    Authors: Tse-Chun Kuo, Hsing-Jien Kung and Jing-Wen Shih
    Citation: Journal of Biomedical Science 2020 27:59
    Content type: Review Published on:

  39. Cardiovascular death is frequently associated with atherosclerosis, a chronic multifactorial disease and a leading cause of death worldwide. Genetically engineered mouse models have proven useful for the study of...

    Authors: Elisardo C Vasquez, Veronica A Peotta, Agata L Gava, Thiago MC Pereira and Silvana S Meyrelles
    Citation: Journal of Biomedical Science 2012 19:22
    Content type: Review Published on:

  40. Infertility, spontaneous abortion and conception of trisomic offspring increase exponentially with age in mammals but in women there is an apparent acceleration in the rate from about age 37. The problems mostly ...

    Authors: Judith H Ford
    Citation: Journal of Biomedical Science 2013 20:93
    Content type: Review Published on:

  41. Early diagnosis of dengue virus infection during the febrile stage is essential for adjusting appropriate management. This study is to identify the predictive markers of clinical and laboratory findings in the...

    Authors: Tzong-Shiann Ho, Shih-Min Wang, Yee-Shin Lin and Ching-Chuan Liu
    Citation: Journal of Biomedical Science 2013 20:75
    Content type: Research Published on:

  42. Mainstay haemophilia treatment, namely intravenous factor replacement, poses several clinical challenges including frequent injections due to the short half-life of recombinant factors, intravenous administration...

    Authors: Dide Okaygoun, Danielle D. Oliveira, Sooriya Soman and Riccardo Williams
    Citation: Journal of Biomedical Science 2021 28:64
    Content type: Review Published on:

  44. Breast cancer is one of the most common malignancies that pose a serious threat to women's health. Reprogramming of energy metabolism is a major feature of the malignant transformation of breast cancer. Compared ...

    Authors: Shiliang Xu, Lingxia Wang, Yuexin Zhao, Tong Mo, Bo Wang, Jun Lin and Huan Yang
    Citation: Journal of Biomedical Science 2024 31:25
    Content type: Review Published on:

  45. Pneumococcal conjugate vaccine (PCV) reduces both invasive pneumococcal disease (IPD) and other pneumococcal infections worldwide. We investigated the impact of stepwise implementation of childhood PCV program...

    Authors: Ching-Fen Shen, Shih-Min Wang, Hsin Chi, Yi-Chuan Huang, Li-Min Huang, Yhu-Chering Huang, Hsiao-Chuan Lin, Yu-Huai Ho, Chao A. Hsiung and Ching-Chuan Liu
    Citation: Journal of Biomedical Science 2020 27:88
    Content type: Research Published on:

  47. Pulmonary diseases due to mycobacteria cause significant morbidity and mortality to human health. In addition to tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), recent epidemiological studies have ...

    Authors: Radha Gopalaswamy, Sivakumar Shanmugam, Rajesh Mondal and Selvakumar Subbian
    Citation: Journal of Biomedical Science 2020 27:74
    Content type: Review Published on:

  49. Huntington’s disease (HD) is one of neurodegenerative diseases, and is defined as a monogenetic disease due to the mutation of Huntingtin...gene. This disease affects several cellular functions in neurons, and fu...

    Authors: Chih-Wei Tung, Pin-Yu Huang, Siew Chin Chan, Pei-Hsun Cheng and Shang-Hsun Yang
    Citation: Journal of Biomedical Science 2021 28:59
    Content type: Review Published on:
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Journal of Biomedical Science

ISSN: 1423-0127