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1058 result(s) for 'antibody' within Journal of Biomedical Science

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  1. Human parvovirus B19 infection has been postulated to the anti-phospholipid syndrome (APS) in autoimmunity. However, the influence of anti-B19-VP1u antibody in autoimmune diseases is still obscure.

    Authors: Chun-Chou Tsai, Bor-Show Tzang, Szu-Yi Chiang, Gwo-Jong Hsu and Tsai-Ching Hsu
    Citation: Journal of Biomedical Science 2009 16:14
    Content type: Research Published on:

  2. Recombinant ZV envelope protein domain III (rZE3) and rLZE3 were prepared with an Escherichia coli...-based system. Dendritic cell surface marker expression and cytokine production upon stimulation were analyzed ...

    Authors: Mei-Yu Chen, Kit Man Chai, Chen-Yi Chiang, Chiao-Chieh Wu, Guann-Yi Yu, Shih-Jen Liu and Hsin-Wei Chen
    Citation: Journal of Biomedical Science 2020 27:51
    Content type: Research Published on:

  4. Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus with a high mutation rate. Importantly, several currently circulating SARS-CoV-2 variant...

    Authors: Kang-Hao Liang, Pao-Yin Chiang, Shih-Han Ko, Yu-Chi Chou, Ruei-Min Lu, Hsiu-Ting Lin, Wan-Yu Chen, Yi-Ling Lin, Mi-Hua Tao, Jia-Tsrong Jan and Han-Chung Wu
    Citation: Journal of Biomedical Science 2021 28:80
    Content type: Research Published on:

  5. The breakdown of BBB with hypertonic arabinose, recombinant tumor necrosis factor-alpha (rTNF-γ), and focused ultrasound (FUS) were used to compare the extent of BBB disruption with rabies virus infection. Specif...

    Authors: Pi-Hung Liao, Hui-Hua Yang, Ping-Tse Chou, Ming-Hseng Wang, Po-Chun Chu, Hao-Li Liu and Li-Kuang Chen
    Citation: Journal of Biomedical Science 2012 19:61
    Content type: Research Published on:

  6. A booster dose of hybrid vaccine in mice previously immunized with wild-type RBD vaccine induced high titers of broadly neutralizing antibodies against all tested SARS-CoV-2 variants ... , hybrid vaccine generate...

    Authors: I-Jung Lee, Cheng-Pu Sun, Ping-Yi Wu, Yu-Hua Lan, I-Hsuan Wang, Wen-Chun Liu, Joyce Pei-Yi Yuan, Yu-Wei Chang, Sheng-Che Tseng, Szu-I Tsung, Yu-Chi Chou, Monika Kumari, Yin-Shiou Lin, Hui-Feng Chen, Tsung-Yen Chen, Chih-Chao Lin…
    Citation: Journal of Biomedical Science 2022 29:49
    Content type: Research Published on:

  9. Therapeutic antibodies are instrumental in improving the treatment outcome ... increasingly explored in this field are pH-responsive antibodies capable of binding target antigens in a ... . We reviewed suitabilit...

    Authors: Tomasz Klaus and Sameer Deshmukh
    Citation: Journal of Biomedical Science 2021 28:11
    Content type: Review Published on:

  10. The developments of antibodies for cancer therapeutics have made remarkable success ... of the biological molecule including origin of the antibody, isotype, affinity, avidity and mechanism of ... progression and...

    Authors: Mukesh Kumar, Akansha Jalota, Sushil Kumar Sahu and Shabirul Haque
    Citation: Journal of Biomedical Science 2024 31:6
    Content type: Review Published on:

  11. It has been more than three decades since the first monoclonal antibody was approved by the United States Food ... ) in 1986, and during this time, antibody engineering has dramatically evolved. Current antibody ...

    Authors: Ruei-Min Lu, Yu-Chyi Hwang, I-Ju Liu, Chi-Chiu Lee, Han-Zen Tsai, Hsin-Jung Li and Han-Chung Wu
    Citation: Journal of Biomedical Science 2020 27:1
    Content type: Review Published on:

  12. Dectin-2, which is a C-type lectin, interacts with the house dust mite (HDM) Dermatophagoides pteronyssinus...allergen. This study aimed to investigate whether Dectin-2 blockade by antagonistic monoclonal antibodies

    Authors: Ming-Han Chen, Ming-Ting Huang, Wen-Kuang Yu, Shinn-Shing Lee, Jia-Horng Wang, Ting-Jen R. Cheng, Michael R. Bowman and Shie-Liang Hsieh
    Citation: Journal of Biomedical Science 2019 26:97
    Content type: Research Published on:

  13. Polyethylene glycol (PEG) is widely used in industry and medicine. Anti-PEG antibodies have been developed for characterizing PEGylated drugs...

    Authors: Cheng-Chung Lee, Yu-Cheng Su, Tzu-Ping Ko, Li-Ling Lin, Chih-Ya Yang, Stanley Shi-Chung Chang, Steve R. Roffler and Andrew H.-J. Wang
    Citation: Journal of Biomedical Science 2020 27:12
    Content type: Research Published on:

  14. The novel coronavirus disease (COVID-19) pandemic remains a global public health crisis, presenting a broad range of challenges. To help address some of the main problems, the scientific community has designed va...

    Authors: Monika Kumari, Ruei-Min Lu, Mu-Chun Li, Jhih-Liang Huang, Fu-Fei Hsu, Shih-Han Ko, Feng-Yi Ke, Shih-Chieh Su, Kang-Hao Liang, Joyce Pei-Yi Yuan, Hsiao-Ling Chiang, Cheng-Pu Sun, I.-Jung Lee, Wen-Shan Li, Hsing-Pang Hsieh, Mi-Hua Tao…
    Citation: Journal of Biomedical Science 2022 29:68
    Content type: Review Published on:

  15. High levels of neutrophil extracellular trap (NET) formation or NETosis and autoantibodies are related to poor prognosis and disease severity of COVID-19 patients. Human angiotensin-converting enzyme 2 (ACE2) cro...

    Authors: Kun-Han Hsieh, Chiao-Hsuan Chao, Yi-Ling Cheng, Yen-Chung Lai, Yung-Chun Chuang, Jen-Ren Wang, Sui-Yuan Chang, Yuan-Pin Hung, Yi-Ming Arthur Chen, Wei-Lun Liu, Woei-Jer Chuang and Trai-Ming Yeh
    Citation: Journal of Biomedical Science 2024 31:39
    Content type: Research Published on:

  16. Calls for the coronavirus to be treated as an endemic illness, such as the flu, are increasing. After achieving high coverage of COVID-19 vaccination, therapeutic drugs have become important for future SARS-CoV-2...

    Authors: Chen-Yi Chiang, Mei-Yu Chen, Chia-Wei Hsu, Chia-Yeh Liu, Yu-Wen Tsai, Hung-Chun Liao, Jia-Ying Yan, Zih-Shiuan Chuang, Hsin-I. Wang, Chien-Hsiung Pan, Chia-Yi Yu, Guann-Yi Yu, Ching-Len Liao, Shih-Jen Liu and Hsin-Wei Chen
    Citation: Journal of Biomedical Science 2022 29:37
    Content type: Research Published on:

  17. The association of functionality and phenotype of follicular helper T cells (Tfh) with dengue virus (DENV) specific antibody responses and clinical disease severity has not...

    Authors: Ayesha Wijesinghe, Jayani Gamage, Hemantha Goonewardena, Laksiri Gomes, Deshni Jayathilaka, Dulharie T. Wijeratne, Ruklanthi de Alwis, Chandima Jeewandara, Ananda Wijewickrama, Graham S. Ogg and Gathsaurie Neelika Malavige
    Citation: Journal of Biomedical Science 2020 27:50
    Content type: Research Published on:

  18. The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public health crisis that demands the timely creation of new therapeutics and viral detection. Owing to their high specificity and reliability, m...

    Authors: Yu-Chyi Hwang, Ruei-Min Lu, Shih-Chieh Su, Pao-Yin Chiang, Shih-Han Ko, Feng-Yi Ke, Kang-Hao Liang, Tzung-Yang Hsieh and Han-Chung Wu
    Citation: Journal of Biomedical Science 2022 29:1
    Content type: Review Published on:

  19. The influenza virus enters the host via hemagglutinin protein binding to cell surface sialic acid. Receptor-mediated endocytosis is followed by viral nucleocapsid uncoating for replication aided by the transmembr...

    Authors: Ujjwal Kumar, Priya Goyal, Zaid K. Madni, Kajal Kamble, Vineet Gaur, Maitreyi S. Rajala and Dinakar M. Salunke
    Citation: Journal of Biomedical Science 2023 30:56
    Content type: Research Published on:

  20. The COVID-19 pandemic continues to pose a significant worldwide threat to human health, as emerging SARS-CoV-2 Omicron variants exhibit resistance to therapeutic antibodies and the ability to evade vaccination-in...

    Authors: Hsiao-Ling Chiang, Kang-Hao Liang, Ruei-Min Lu, Ting-Wen Kuo, Yi‑Ling Lin and Han-Chung Wu
    Citation: Journal of Biomedical Science 2023 30:59
    Content type: Research Published on:

  22. Very few studies have identified receptor molecules for dengue virus (DENV) on neural cells. This study was designed to identify putative receptor/(s) involved in entry of DENV-3 in human neural cells of vario...

    Authors: Amita Sharma, Ravi Vasanthapuram, Manjunatha M Venkataswamy and Anita Desai
    Citation: Journal of Biomedical Science 2020 27:55
    Content type: Research Published on:

  23. Passive immunization with JEV-NTE-immunized sera or DV/ZV-NTE-immunized sera could increase the survival rate or prolong the survival time in JEV-challenged ICR mice and reduce the viremia levels significantly in...

    Authors: Li-Chen Yen, Hsin-Wei Chen, Chia-Lo Ho, Chang-Chi Lin, Yi-Ling Lin, Qiao-Wen Yang, Kuo-Chou Chiu, Shu-Pei Lien, Ren-Jye Lin and Ching-Len Liao
    Citation: Journal of Biomedical Science 2023 30:41
    Content type: Research Published on:

  24. In this study, we developed a non-genetic engineering technology for rapidly manufacturing a large amount of cancer-specific T cells by utilizing a unique anti-cancer/anti-CD3 bispecific antibody (BsAb) to direct...

    Authors: Yi-Jou Chen, Michael Chen, Tian-Lu Cheng, Yi-Shan Tsai, Chang-Hung Wang, Che-Yi Chen, Tung-Yun Wu, Shey-Cherng Tzou, Kai-Hung Wang, Jing-Jy Cheng, An-Pei Kao, Shyr-Yi Lin and Kuo-Hsiang Chuang
    Citation: Journal of Biomedical Science 2023 30:35
    Content type: Research Published on:

  25. Hairy and Enhancer of split 1 (Hes-1) is a transcriptional repressor that plays an important role in neuronal differentiation and development, but post-translational modifications of Hes-1 are much less known. In...

    Authors: Hsin-Ying Clair Chiou, Shau-Yu Liu, Cheng-Hsiung Lin and Eminy HY Lee
    Citation: Journal of Biomedical Science 2014 21:53
    Content type: Research Published on:

  26. Both H1N1 and H5N1 induced significant homologous IgG, HAI, and microneutralization antibody responses in the mice, while only vaccines ... plus adjuvant produced significant heterogeneous IgG and HAI antibody re...

    Authors: Hui-Tsu Lin, Chuan-Chang Chuang, Hsieh-Ling Wu, Der-Ming Chu and Yeau-Ching Wang
    Citation: Journal of Biomedical Science 2013 20:19
    Content type: Research Published on:

  27. The variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) harbor diverse spike (S) protein sequences, which can greatly influence the efficacies of therapeutics. Therefore, it would be of great...

    Authors: Shih-Han Ko, Wan-Yu Chen, Shih-Chieh Su, Hsiu-Ting Lin, Feng-Yi Ke, Kang-Hao Liang, Fu-Fei Hsu, Monika Kumari, Chi-Yu Fu and Han-Chung Wu
    Citation: Journal of Biomedical Science 2022 29:108
    Content type: Research Published on:

  28. Bt18 parasporal protein was separated using Mono Q anion exchange column attached to a HPLC system and antibody was raised against the purified 68-kDa...

    Authors: Kanakeswary Krishnan, Jeremy Er An Ker, Shar Mariam Mohammed and Vishna Devi Nadarajah
    Citation: Journal of Biomedical Science 2010 17:86
    Content type: Research Published on:

  29. Different neurological disorders frequently display antibodies against several self-glycans. Increasing evidence supports ... less is known about their origin. Meanwhile, antibodies recognizing non-self glycans a...

    Authors: Ricardo Dante Lardone, Fernando José Irazoqui and Gustavo Alejandro Nores
    Citation: Journal of Biomedical Science 2019 26:67
    Content type: Research Published on:

  30. Dengue virus (DENV) infection can cause life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Vascular leakage and abnormal hemorrhage are the two major pathogenic changes found in thes...

    Authors: Yung-Chun Chuang, Shu-Ying Wang, Yee-Shin Lin, Hong-Ru Chen and Trai-Ming Yeh
    Citation: Journal of Biomedical Science 2013 20:42
    Content type: Review Published on:

  31. The membrane-proximal external region (MPER) of HIV-1 gp41 is particularly conserved and target for the potent broadly neutralizing monoclonal antibodies (bnMAbs) 2F5, 4E10 and 10E8....

    Authors: Thomas D Benen, Paul Tonks, Alexander Kliche, Ruth Kapzan, Jonathan L Heeney and Ralf Wagner
    Citation: Journal of Biomedical Science 2014 21:79
    Content type: Research Published on:

  32. Coronavirus Disease 2019 (COVID-19) has been the most severe public health challenge in this century. Two years after its emergence, the rapid development and deployment of effective COVID-19 vaccines have suc...

    Authors: Wei-Yu Chi, Yen-Der Li, Hsin-Che Huang, Timothy En Haw Chan, Sih-Yao Chow, Jun-Han Su, Louise Ferrall, Chien-Fu Hung and T.-C. Wu
    Citation: Journal of Biomedical Science 2022 29:82
    Content type: Review Published on:

  33. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the most challenging pandemic in this century. Cons...

    Authors: Yen-Der Li, Wei-Yu Chi, Jun-Han Su, Louise Ferrall, Chien-Fu Hung and T.-C. Wu
    Citation: Journal of Biomedical Science 2020 27:104
    Content type: Review Published on:

  34. To find disease-specific B-cell epitopes that correspond to or mimic natural epitopes, we used phage display technology to determine the targets of specific antibodies present in the sera of immune-responsive ......

    Authors: Jing-You Guo, I-Ju Liu, Hsiu-Ting Lin, Mei-Jung Wang, Yu-Ling Chang, Shin-Chang Lin, Mei-Ying Liao, Wei-Chia Hsu, Yi-Ling Lin, James C. Liao and Han-Chung Wu
    Citation: Journal of Biomedical Science 2021 28:43
    Content type: Research Published on:

  35. The central molecule in the pathogenesis of Alzheimer’s disease (AD) is believed to be a small-sized polypeptide – beta amyloid (Aβ) which has an ability to assemble spontaneously into oligomers. Various studies ...

    Authors: Indre Dalgediene, Rita Lasickiene, Rima Budvytyte, Gintaras Valincius, Ramune Morkuniene, Vilmante Borutaite and Aurelija Zvirbliene
    Citation: Journal of Biomedical Science 2013 20:10
    Content type: Research Published on:

  36. Matrix metalloproteinase-9 (MMP-9) has been shown to be induced by cytokines including TNF-α and may contribute to bone inflammatory diseases. However, the mechanisms underlying MMP-9 expression induced by TNF...

    Authors: Chia-Lan Tsai, Wei-Chung Chen, Hsi-Lung Hsieh, Pei-Ling Chi, Li-Der Hsiao and Chuen-Mao Yang
    Citation: Journal of Biomedical Science 2014 21:12
    Content type: Research Published on:

    The Erratum to this article has been published in Journal of Biomedical Science 2015 22:20

  38. Albumin-conjugated FLT3L (Alb-FLT3L) was generated and applied for translational medicine purposes; here it was used to treat naïve C57BL/6 and OT1 mice for CD8 T cell response analysis. Syngeneic B16ova and E...

    Authors: Hsin-Fang Tu, Yu-Jui Kung, Ling Lim, Julia Tao, Ming-Hung Hu, Michelle Cheng, Deyin Xing, T. C. Wu and Chien-Fu Hung
    Citation: Journal of Biomedical Science 2024 31:19
    Content type: Research Published on:

  39. Dry eye disease (DED) is a common disease in ophthalmology, affecting millions of people worldwide. Recent studies have shown that inflammation is the core mechanism of DED. IL-20 is a proinflammatory cytokine in...

    Authors: Hsiao-Hsuan Wang, Wei-Yu Chen, Yi-Hsun Huang, Sheng-Min Hsu, Yeou-Ping Tsao, Yu-Hsiang Hsu and Ming-Shi Chang
    Citation: Journal of Biomedical Science 2022 29:36
    Content type: Research Published on:

  40. CD73 functions in EGFR-mediated tumor cell dissemination were addressed in 2D and 3D cellular models of migration and invasion. The novel antagonizing antibody 22E6 and therapeutic antibody Cetuximab served as in...

    Authors: Enxian Shi, Zhengquan Wu, Birnur Sinem Karaoglan, Sabina Schwenk-Zieger, Gisela Kranz, Nilofer Abdul Razak, Christoph A. Reichel, Martin Canis, Philipp Baumeister, Reinhard Zeidler and Olivier Gires
    Citation: Journal of Biomedical Science 2023 30:72
    Content type: Research Published on:

  41. Dengue is an important mosquito-borne viral infection that affects millions of persons worldwide. Early diagnosis is necessary to effect appropriate management and decrease mortality. Immunochromatographic tes...

    Authors: Ivan E. Vickers, Kevin M. Harvey, Michelle G. Brown, Kereann Nelson, Marion Bullock DuCasse and John F. Lindo
    Citation: Journal of Biomedical Science 2015 22:55
    Content type: Research Published on:

  43. mTOR is a genetically conserved serine/threonine protein kinase, which controls cell growth, proliferation, and survival. A multifunctional protein CAD, catalyzing the initial three steps in de novo pyrimidine sy...

    Authors: Akio Nakashima, Ippei Kawanishi, Sumiko Eguchi, Eugene Hsin Yu, Satoshi Eguchi, Noriko Oshiro, Ken-ichi Yoshino, Ushio Kikkawa and Kazuyoshi Yonezawa
    Citation: Journal of Biomedical Science 2013 20:24
    Content type: Research Published on:

  44. The phosphorylation site of ROCKI sensitive to its inhibition was identified to be the Ser1333 residue. The ROCKI pSer1333-specific antibody does not cross-react with phosphorylated ROCKII....

    Authors: Hsiang-Hao Chuang, Shao-Wei Liang, Zee-Fen Chang and Hsiao-Hui Lee
    Citation: Journal of Biomedical Science 2013 20:83
    Content type: Research Published on:

  45. Infections by viruses including severe acute respiratory syndrome coronavirus 2 could cause organ inflammations such as myocarditis, pneumonia and encephalitis. Innate immunity to viral nucleic acids mediates ...

    Authors: Mingli Fang, Ao Zhang, Yong Du, Wenting Lu, Junying Wang, Laurie J. Minze, Timothy C. Cox, Xian Chang Li, Junji Xing and Zhiqiang Zhang
    Citation: Journal of Biomedical Science 2022 29:55
    Content type: Research Published on:

  46. Cyclic stretch significantly increased TLR4 protein and mRNA expression after 2 h to 24 h of stretch. Addition of SB203580, TNF-α antibody, and p38α MAP kinase siRNA 30 min ... cyclic stretch could be supershifte...

    Authors: Kou-Gi Shyu, Bao-Wei Wang, Chiu-Mei Lin and Hang Chang
    Citation: Journal of Biomedical Science 2010 17:15
    Content type: Research Published on:

  47. Influenza is one of the most important viral infections globally. Viral RNA-dependent RNA polymerase (RdRp) consists of the PA, PB1, and PB2 subunits, and the amino acid residues of each subunit are highly con...

    Authors: Mei-Lin Yang, Yi-Cheng Chen, Chung-Teng Wang, Hao-Earn Chong, Nai-Hui Chung, Chia-Hsing Leu, Fu-Tong Liu, Michael M. C. Lai, Pin Ling, Chao-Liang Wu and Ai-Li Shiau
    Citation: Journal of Biomedical Science 2023 30:14
    Content type: Research Published on:

  48. Insufficient clearance of soluble oligomeric amyloid-β peptide (oAβ) in the central nervous system leads to the synaptic and memory deficits in Alzheimer's disease (AD). Previously we have identified scavenger...

    Authors: Fong-Lee Huang, Young-Ji Shiao, Sheue-Jane Hou, Cheng-Ning Yang, Yi-Jen Chen, Chao-Hsiung Lin, Feng-Shiun Shie and Huey-Jen Tsay
    Citation: Journal of Biomedical Science 2013 20:54
    Content type: Research Published on:

  49. Hepatitis B virus (HBV) persistently infected about 250 million people worldwide, and a curative treatment remains an unmet medical need. Among many approaches to treat chronic hepatitis B (CHB), therapeutic v...

    Authors: Jau-Hau Horng, Wei-Hsiang Lin, Chang-Ru Wu, You-Yu Lin, Li-Ling Wu, Ding-Shinn Chen and Pei-Jer Chen
    Citation: Journal of Biomedical Science 2020 27:70
    Content type: Research Published on:

  50. EV-A71 infection transiently increased serum and brain IL-6 protein levels in mice. Most importantly, absence of IL-6 due to gene knockout or depletion of IL-6 using neutralizing monoclonal antibody enhanced the ...

    Authors: Li-Chiu Wang, Hui-Wen Yao, Chuan-Fa Chang, Shainn-Wei Wang, Shih-Min Wang and Shun-Hua Chen
    Citation: Journal of Biomedical Science 2017 24:94
    Content type: Research Published on:
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Journal of Biomedical Science

ISSN: 1423-0127