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27 result(s) for 'autism' within Journal of Biomedical Science

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  1. Dendritic spines, the actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain. Many actin-regulating molecules modulate dendritic spine morpholo...

    Authors: Hsiao-Tang Hu, Tzyy-Nan Huang and Yi-Ping Hsueh
    Citation: Journal of Biomedical Science 2020 27:103
    Content type: Research Published on:

  3. Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), appear to recapitulate the brain’s 3D cy...

    Authors: Chun-Ting Lee, Raphael M. Bendriem, Wells W. Wu and Rong-Fong Shen
    Citation: Journal of Biomedical Science 2017 24:59
    Content type: Review Published on:

  4. Disruption of normal brain development is implicated in numerous psychiatric disorders with neurodevelopmental origins, including autism spectrum disorder (ASD). Widespread abnormalities in...A receptors (GABAARs...

    Authors: Ming-Chia Chu, Han-Fang Wu, Chi-Wei Lee, Yueh-Jung Chung, Hsiang Chi, Po See Chen and Hui-Ching Lin
    Citation: Journal of Biomedical Science 2022 29:51
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Biomedical Science 2023 30:11

  5. To the best of our knowledge, this is the first report to indicate the reduced death of NPCs by VPA at developmentally critical periods through the degradation of IκBα and the activation of NF-κB signaling. The r...

    Authors: Hyo Sang Go, Jung Eun Seo, Ki Chan Kim, So Min Han, Pitna Kim, Young Sun Kang, Seol Heui Han, Chan Young Shin and Kwang Ho Ko
    Citation: Journal of Biomedical Science 2011 18:48
    Content type: Research Published on:

  6. Sarcosine, a glycine transporter type 1 inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site, potentiates NMDA receptor function. Structurally similar to sarcosine, N,N-...

    Authors: Mei-Yi Lee, Yi-Ruu Lin, Yi-Shu Tu, Yufeng Jane Tseng, Ming-Huan Chan and Hwei-Hsien Chen
    Citation: Journal of Biomedical Science 2017 24:18
    Content type: Research Published on:

  9. Fragile X Syndrome is the most common known genetic cause of autism. The Fmr1...-KO mouse, lacks the fragile X mental retardation protein (FMRP), and is used as a model of the syndrome. The core behavioral defici...

    Authors: Abdeslem El Idrissi, Lorenz S Neuwirth and William L’Amoreaux
    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S15
    Content type: Review Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  10. The endoplasmic reticulum (ER) is the biggest organelle in cells and is involved in versatile cellular processes. Formation and maintenance of ER morphology are regulated by a series of proteins controlling me...

    Authors: Yu-Tzu Shih and Yi-Ping Hsueh
    Citation: Journal of Biomedical Science 2018 25:2
    Content type: Review Published on:

  11. Toll-like receptors (TLRs) are well known as critical pattern recognition receptors that trigger innate immune responses. In addition, TLRs are expressed in neurons and may act as the gears in the neuronal det...

    Authors: Chiung-Ya Chen, Yi-Chun Shih, Yun-Fen Hung and Yi-Ping Hsueh
    Citation: Journal of Biomedical Science 2019 26:90
    Content type: Review Published on:

  12. Both Neurofibromatosis type I (NF1) and inclusion body myopathy with Paget's disease of bone and frontotemporal dementia (IBMPFD) are autosomal dominant genetic disorders. These two diseases are fully penetran...

    Authors: Yi-Ping Hsueh
    Citation: Journal of Biomedical Science 2012 19:33
    Content type: Review Published on:

  14. The field of regenerative medicine has witnessed remarkable advancements with the emergence of induced pluripotent stem cells (iPSCs) derived from a variety of sources. Among these, urine-derived induced pluri...

    Authors: Xiya Yin, Qingfeng Li, Yan Shu, Hongbing Wang, Biju Thomas, Joshua T. Maxwell and Yuanyuan Zhang
    Citation: Journal of Biomedical Science 2024 31:47
    Content type: Review Published on:

  15. Valproic acid, a widely used anticonvulsant drug, is a potent teratogen resulting in various congenital abnormalities. However, the mechanisms underlying valproic acid induced teratogenesis are nor clear. Rece...

    Authors: Gang Wu, Changlong Nan, Johnathon C Rollo, Xupei Huang and Jie Tian
    Citation: Journal of Biomedical Science 2010 17:16
    Content type: Research Published on:

  18. Social recognition memory (SRM) is the ability to distinguish familiar from novel conspecifics and is crucial for survival and reproductive success across social species. We previously reported that oxytocin (...

    Authors: Tsung-Chih Tsai, Yi-Syuan Fang, Yu-Chieh Hung, Ling-Chien Hung and Kuei-Sen Hsu
    Citation: Journal of Biomedical Science 2022 29:50
    Content type: Research Published on:

  19. Fragile X syndrome (FXS), the most commonly inherited mental retardation and single gene cause of autistic spectrum disorder, occurs when the Fmr1 gene is mutated. The product of Fmr1, fragile X linked mental ...

    Authors: Se Jin Jeon, Jung Eun Seo, Sung-Il Yang, Ji Woong Choi, David Wells, Chan Young Shin and Kwang Ho Ko
    Citation: Journal of Biomedical Science 2011 18:17
    Content type: Research Published on:

  20. Glucose homeostasis in humans is an important factor for the functioning of nervous system. Hypoglycemia and hyperglycemia is found to be associated with central and peripheral nerve system dysfunction. Change...

    Authors: Sherin Antony, Peeyush Kumar T, Jobin Mathew, TR Anju and CS Paulose
    Citation: Journal of Biomedical Science 2010 17:7
    Content type: Research Published on:

  22. Alzheimer’s disease (AD) is characterized by progressive memory and neuronal loss culminating in cognitive impairment that not only affects a person’s living ability but also becomes a society’s as well as a f...

    Authors: Ya-Hsin Hsiao, Chih-Hua Chang and Po-Wu Gean
    Citation: Journal of Biomedical Science 2018 25:3
    Content type: Review Published on:

  23. Down syndrome (DS), caused by triplication of human chromosome 21, is the most common aneuploidies. The main characteristic of DS patients is intellectual disability. MicroRNAs (miRNAs) play important regulato...

    Authors: Wei-li Shi, Zhong-zhen Liu, Hong-dan Wang, Dong Wu, Hui Zhang, Hai Xiao, Yan Chu, Qiao-fang Hou and Shi-xiu Liao
    Citation: Journal of Biomedical Science 2016 23:48
    Content type: Research Published on:

  25. Gut microbiota interacting with an intact mucosal surface are key to the maintenance of homeostasis and health. This review discusses the current state of knowledge of the biofilm mode of growth of these micro...

    Authors: Andre Gerald Buret, Jean-Paul Motta, Thibault Allain, Jose Ferraz and John Lawrence Wallace
    Citation: Journal of Biomedical Science 2019 26:1
    Content type: Review Published on:

  26. Sudden cardiac death (SCD) describes a natural and unexpected death from cardiac causes occurring within a short period of time (generally within 1 h of symptom onset) in the absence of any other potentially l...

    Authors: Simona Magi, Vincenzo Lariccia, Marta Maiolino, Salvatore Amoroso and Santo Gratteri
    Citation: Journal of Biomedical Science 2017 24:56
    Content type: Review Published on:

  27. Dysbiosis of gut microbiota is closely related to occurrence of many important chronic inflammations-related diseases. So far the traditionally prescribed prebiotics and probiotics do not show significant impa...

    Authors: Yu-Ling Tsai, Tzu-Lung Lin, Chih-Jung Chang, Tsung-Ru Wu, Wei-Fan Lai, Chia-Chen Lu and Hsin-Chih Lai
    Citation: Journal of Biomedical Science 2019 26:3
    Content type: Review Published on:
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Journal of Biomedical Science

ISSN: 1423-0127