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835 result(s) for 'review' within Journal of Biomedical Science

Page 4 of 17

  2. Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each yea...

    Authors: Saumya Sinha, Kinjal Singh, Y. S. Ravi Kumar, Riya Roy, Sushant Phadnis, Varsha Meena, Sankar Bhattacharyya and Bhupendra Verma
    Citation: Journal of Biomedical Science 2024 31:43
    Content type: Review Published on:

  3. Streptococcus pyogenes (group A streptococcus, GAS) causes a variety of diseases ranging from mild superficial infections of the throat and skin to severe invasive infections, such as necrotizing soft tissue infe...

    Authors: Lea A. Tölken, Antje D. Paulikat, Lana H. Jachmann, Alexander Reder, Manuela Gesell Salazar, Laura M. Palma Medina, Stephan Michalik, Uwe Völker, Mattias Svensson, Anna Norrby-Teglund, Katharina J. Hoff, Michael Lammers and Nikolai Siemens
    Citation: Journal of Biomedical Science 2024 31:26
    Content type: Research Published on:

  4. The novel coronavirus disease (COVID-19) pandemic remains a global public health crisis, presenting a broad range of challenges. To help address some of the main problems, the scientific community has designed va...

    Authors: Monika Kumari, Ruei-Min Lu, Mu-Chun Li, Jhih-Liang Huang, Fu-Fei Hsu, Shih-Han Ko, Feng-Yi Ke, Shih-Chieh Su, Kang-Hao Liang, Joyce Pei-Yi Yuan, Hsiao-Ling Chiang, Cheng-Pu Sun, I.-Jung Lee, Wen-Shan Li, Hsing-Pang Hsieh, Mi-Hua Tao…
    Citation: Journal of Biomedical Science 2022 29:68
    Content type: Review Published on:

  5. In the past decade, single-cell technologies have revealed the heterogeneity of the tumor-immune microenvironment at the genomic, transcriptomic, and proteomic levels and have furthered our understanding of the m...

    Authors: Wan-Chen Hsieh, Bugi Ratno Budiarto, Yi-Fu Wang, Chih-Yu Lin, Mao-Chun Gwo, Dorothy Kazuno So, Yi-Shiuan Tzeng and Shih-Yu Chen
    Citation: Journal of Biomedical Science 2022 29:96
    Content type: Review Published on:

  6. The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public health crisis that demands the timely creation of new therapeutics and viral detection. Owing to their high specificity and reliability...

    Authors: Yu-Chyi Hwang, Ruei-Min Lu, Shih-Chieh Su, Pao-Yin Chiang, Shih-Han Ko, Feng-Yi Ke, Kang-Hao Liang, Tzung-Yang Hsieh and Han-Chung Wu
    Citation: Journal of Biomedical Science 2022 29:1
    Content type: Review Published on:

  7. With the advances in deep sequencing-based transcriptome profiling technology, it is now known that human genome is transcribed more pervasively than previously thought. Up to 90% of the human DNA is transcribed,...

    Authors: Chih-Fan Yeh, Yu-Chen Eugene Chang, Cheng-Yuan Lu, Chin-Feng Hsuan, Wei-Tien Chang and Kai-Chien Yang
    Citation: Journal of Biomedical Science 2020 27:48
    Content type: Review Published on:

  8. MicroRNAs (miRNAs) are involved in multiple biological activities as well as disease progression including cancer. Interestingly, miRNAs could act as either tumor suppressors or oncogenes depending on the functio...

    Authors: Pai-Sheng Chen, Jen-Liang Su and Mien-Chie Hung
    Citation: Journal of Biomedical Science 2012 19:90
    Content type: Review Published on:

  9. Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably severe pulmonary symptoms, cardiac ...

    Authors: Alain C. Borczuk and Rhonda K. Yantiss
    Citation: Journal of Biomedical Science 2022 29:87
    Content type: Review Published on:

  11. Resistance to conventional anticancer therapies in patients with advanced solid tumors has prompted the need of alternative cancer therapies. Moreover, the success of novel cancer therapies depends on their se...

    Authors: S Patyar, R Joshi, DS Prasad Byrav, A Prakash, B Medhi and BK Das
    Citation: Journal of Biomedical Science 2010 17:21
    Content type: Review Published on:

  12. Infection with dengue virus (DENV) causes both mild dengue fever and severe dengue diseases, such as dengue hemorrhagic fever and dengue shock syndrome. The pathogenic mechanisms for DENV are complicated, involvi...

    Authors: Tsung-Ting Tsai, Yi-Jui Chuang, Yee-Shin Lin, Shu-Wen Wan, Chia-Ling Chen and Chiou-Feng Lin
    Citation: Journal of Biomedical Science 2013 20:40
    Content type: Review Published on:

  13. The SCUBE [Signal peptide-Complement C1r/C1s, Uegf, Bmp1 (CUB)-Epithelial growth factor domain-containing protein] family consists of three proteins in vertebrates, SCUBE1, 2 and 3, which are highly conserved ...

    Authors: Yuh-Charn Lin, Binay K. Sahoo, Shiang-Shin Gau and Ruey-Bing Yang
    Citation: Journal of Biomedical Science 2023 30:33
    Content type: Review Published on:

  14. Thyroid hormone analogues—particularly, l-thyroxine (T4) has been shown to be relevant to the functions of a variety of cancers. Integrin αvβ3 is a plasma membrane structural protein linked to signal transduction...

    Authors: Yu-Chen S. H. Yang, Po-Jui Ko, Yi-Shin Pan, Hung-Yun Lin, Jacqueline Whang-Peng, Paul J. Davis and Kuan Wang
    Citation: Journal of Biomedical Science 2021 28:24
    Content type: Review Published on:

  15. Mitochondria are sub-cellular organelles that produce adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS). As suggested over 70 years ago by Otto Warburg and recently confirmed with molecular ...

    Authors: Anna M Czarnecka, Jerzy S Czarnecki, Wojciech Kukwa, Francesco Cappello, Anna Ścińska and Andrzej Kukwa
    Citation: Journal of Biomedical Science 2010 17:31
    Content type: Review Published on:

  18. Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor expressed on the surface of T cells. High expression of PD-1 leads to T-cell dysfunction in the tumor microenvironment (TME). However, th...

    Authors: Wan-Ting Kuo, I-Ying Kuo, Hung-Chia Hsieh, Ssu-Ting Wu, Wu-Chou Su and Yi-Ching Wang
    Citation: Journal of Biomedical Science 2024 31:20
    Content type: Research Published on:

  19. Esophageal squamous cell carcinoma (ESCC) is the sixth leading cause of cancer-associated death worldwide with a dismal overall 5-year survival rate of less than 20%. The standard first-line therapy for advanc...

    Authors: Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan and Yi-Ching Wang
    Citation: Journal of Biomedical Science 2022 29:90
    Content type: Research Published on:

  20. Increasing evidence suggests that immune responses are involved in the control of cancer and that the immune system can be manipulated in different ways to recognize and attack tumors. Progress in immune-based st...

    Authors: Pablo Matar, Laura Alaniz, Viviana Rozados, Jorge B Aquino, Mariana Malvicini, Catalina Atorrasagasti, Manuel Gidekel, Marcelo Silva, O Graciela Scharovsky and Guillermo Mazzolini
    Citation: Journal of Biomedical Science 2009 16:30
    Content type: Review Published on:

  21. Reversible cerebral vasoconstriction syndrome (RCVS) is a complex neurovascular disorder being recognized during the past two decades. It is characterized by multiple abrupt severe headaches and widespread cerebr...

    Authors: Shih-Pin Chen and Shuu-Jiun Wang
    Citation: Journal of Biomedical Science 2022 29:72
    Content type: Review Published on:

  22. Whether microgravity might influence tumour growth and carcinogenesis is still an open issue. It is not clear also if and how normal and transformed cells are differently solicited by microgravity. The present...

    Authors: Paola Cuccarolo, Francesca Barbieri, Monica Sancandi, Silvia Viaggi and Paolo Degan
    Citation: Journal of Biomedical Science 2010 17:63
    Content type: Research Published on:

  23. The tumor immune microenvironment represents a sophisticated ecosystem where various immune cell subtypes communicate with cancer cells and stromal cells. The dynamic cellular composition and functional character...

    Authors: Feng-Ming Tien, Hsuan-Hsuan Lu, Shu-Yung Lin and Hsing-Chen Tsai
    Citation: Journal of Biomedical Science 2023 30:3
    Content type: Review Published on:

  25. The efficiency of regenerative medicine can be ameliorated by improving the biological performances of stem cells before their transplantation. Several ex-vivo protocols of non-damaging cell hypoxia have been dem...

    Authors: Claudio Muscari, Emanuele Giordano, Francesca Bonafè, Marco Govoni, Alice Pasini and Carlo Guarnieri
    Citation: Journal of Biomedical Science 2013 20:63
    Content type: Review Published on:

  26. Human Papillomavirus type 16 (HPV16) has been associated with a subset of head and neck cancers. Two HPV encoded oncogenic proteins, E6 and E7, are important for the malignant progression of HPV-associated can...

    Authors: Ssu-Hsueh Tseng, Li Liu, Shiwen Peng, Jinhwi Kim, Louise Ferrall, Chien-Fu Hung and T. -C. Wu
    Citation: Journal of Biomedical Science 2021 28:63
    Content type: Research Published on:

  28. The mechanistic target of rapamycin complex 1 (mTORC1) is an essential regulator of cell growth and metabolism through the modulation of protein and lipid synthesis, lysosome biogenesis, and autophagy. The activi...

    Authors: Terunao Takahara, Yuna Amemiya, Risa Sugiyama, Masatoshi Maki and Hideki Shibata
    Citation: Journal of Biomedical Science 2020 27:87
    Content type: Review Published on:

  29. Blood pressure control with renin-angiotensin system (RAS) blockade has remained the gold standard for treating patients with proteinuric chronic kidney disease (CKD) up to date. Nevertheless, RAS blockade slows ...

    Authors: Yung-Ming Chen, Wen-Chih Chiang, Shuei-Liong Lin and Tun-Jun Tsai
    Citation: Journal of Biomedical Science 2017 24:84
    Content type: Review Published on:

  30. Adrenomedullin (ADM) exerts its biological functions through the receptor-mediated enzymatic mechanisms that involve protein kinase A (PKA), or neuronal nitric oxide synthase (nNOS). We previously demonstrated...

    Authors: David HT Yen, Lih-Chi Chen, Yuh-Chiang Shen, Ying-Chen Chiu, I-Chun Ho, Ya-Jou Lou, I-Chin Chen and Jiin-Cherng Yen
    Citation: Journal of Biomedical Science 2011 18:32
    Content type: Research Published on:

  32. Enterovirus A71 (EV-A71) is one of the causative pathogens of hand, foot, and mouth disease (HFMD), which may cause severe neurological and cardiopulmonary complications in children. In this review, we discuss th...

    Authors: Shao-Hsuan Hsia, Jainn-Jim Lin, Oi-Wa Chan and Tzou-Yien Lin
    Citation: Journal of Biomedical Science 2020 27:53
    Content type: Review Published on:

  33. Mucopolysaccharidoses (MPS) are inherited metabolic disorders caused by mutations leading to dysfunction of one of enzymes involved in degradation of glycosaminoglycans (GAGs). Due to their impaired degradatio...

    Authors: Joanna Jakóbkiewicz-Banecka, Ewa Piotrowska, Magdalena Narajczyk, Sylwia Barańska and Grzegorz Węgrzyn
    Citation: Journal of Biomedical Science 2009 16:26
    Content type: Research Published on:

  35. Human Papillomavirus type 18 (HPV18) is a high-risk HPV that is commonly associated with cervical cancer. HPV18 oncogenes E6 and E7 are associated with the malignant transformation of cells, thus the identific...

    Authors: Shiwen Peng, Deyin Xing, Louise Ferrall, Ya-Chea Tsai, Chien-Fu Hung and T.-C. Wu
    Citation: Journal of Biomedical Science 2022 29:80
    Content type: Research Published on:

  36. Genome-wide association studies (GWASs) have linked RRBP1 (ribosomal-binding protein 1) genetic variants to atherosclerotic cardiovascular diseases and serum lipoprotein levels. However, how RRBP1 regulates blood...

    Authors: Chu-Hsuan Chiu, Chin-Feng Hsuan, Shih-Hua Lin, Yi-Jen Hung, Chii-Min Hwu, Siow-Wey Hee, Shu-Wha Lin, Sitt-Wai Fong, Patrick Ching-Ho Hsieh, Wei-Shun Yang, Wei-Chou Lin, Hsiao-Lin Lee, Meng-Lun Hsieh, Wen-Yi Li, Jou-Wei Lin, Chih-Neng Hsu…
    Citation: Journal of Biomedical Science 2023 30:13
    Content type: Research Published on:

  37. To characterize single nucleotide polymorphisms (SNPs) within the promoter region of the estrogen receptor beta (ERβ) gene and to analyze the association of ERβ SNPs with susceptibility to breast cancer. Genot...

    Authors: Li Chen, Yan Liang, Juhui Qiu, Lingling Zhang, Xianchun Chen, Xiangdong Luo and Jun Jiang
    Citation: Journal of Biomedical Science 2013 20:32
    Content type: Research Published on:

  38. Electrical impulses from cardiac pacemaker cardiomyocytes initiate cardiac contraction and blood pumping and maintain life. Abnormal electrical impulses bring patients with low heart rates to cardiac arrest. The ...

    Authors: Chih-Min Liu, Yi-Chun Chen and Yu-Feng Hu
    Citation: Journal of Biomedical Science 2023 30:74
    Content type: Review Published on:

  39. Phenotypic heterogeneity is very common in genetic systems and in human diseases and has important consequences for disease diagnosis and treatment. In addition to the many genetic and non-genetic (e.g., epige...

    Authors: Y. Henry Sun, Yueh-Lin Wu and Ben-Yang Liao
    Citation: Journal of Biomedical Science 2023 30:58
    Content type: Review Published on:

  41. Circular RNAs (circRNAs) represent a class of non-coding RNAs (ncRNAs) which are widely expressed in mammals and tissue-specific, of which some could act as critical regulators in the atherogenesis of cerebrov...

    Authors: Shanchao Zhang, Guixiang Song, Jing Yuan, Shan Qiao, Shan Xu, Zhihua Si, Yang Yang, Xuxu Xu and Aihua Wang
    Citation: Journal of Biomedical Science 2020 27:11
    Content type: Research Published on:

  42. Hyaluronan (HA) is abundantly expressed in several human tissues and a variety of roles for HA has been highlighted. Particularly relevant for tissue repair, HA is actively produced during tissue injury, as wi...

    Authors: Francesca Bonafè, Marco Govoni, Emanuele Giordano, Claudio Marcello Caldarera, Carlo Guarnieri and Claudio Muscari
    Citation: Journal of Biomedical Science 2014 21:100
    Content type: Review Published on:

  44. Unlike preventative vaccines, therapeutic vaccines aim to generate cell-mediated immunity. HPV oncoproteins E6 and E7 are responsible for the malignant progression of HPV-associated diseases and are consistently ...

    Authors: Andrew Yang, Emily Farmer, T. C. Wu and Chien-Fu Hung
    Citation: Journal of Biomedical Science 2016 23:75
    Content type: Review Published on:

  47. Taurine demonstrates multiple cellular functions including a central role as a neurotransmitter, as a trophic factor in CNS development, in maintaining the structural integrity of the membrane, in regulating c...

    Authors: Jang-Yen Wu and Howard Prentice
    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S1
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  48. Mesenchymal stem cells (MSCs) have been demonstrated to have a great potential in the treatment of several diseases due to their differentiation and immunomodulatory capabilities and their ability to be easily cu...

    Authors: Jana Janockova, Lucia Slovinska, Denisa Harvanova, Timea Spakova and Jan Rosocha
    Citation: Journal of Biomedical Science 2021 28:39
    Content type: Review Published on:

  49. Gram-positive (G+) bacterial infection is a great burden to both healthcare and community medical resources. As a result of the increasing prevalence of multidrug-resistant G+ bacteria such as methicillin-resista...

    Authors: He Liu, Zhen Hu, Mengyang Li, Yi Yang, Shuguang Lu and Xiancai Rao
    Citation: Journal of Biomedical Science 2023 30:29
    Content type: Review Published on:

  50. Breast cancer is the most diagnosed malignancy in women. Increasing evidence has highlighted the importance of chronic inflammation at the local and/or systemic level in breast cancer pathobiology, influencing it...

    Authors: Sara Socorro Faria, Susan Costantini, Vladmir Cláudio Cordeiro de Lima, Victor Pianna de Andrade, Mickaël Rialland, Rebe Cedric, Alfredo Budillon and Kelly Grace Magalhães
    Citation: Journal of Biomedical Science 2021 28:26
    Content type: Review Published on:
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Journal of Biomedical Science

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