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835 result(s) for 'review' within Journal of Biomedical Science

Page 5 of 17

  1. Severe cutaneous adverse drug reactions (SCARs) are a group of serious clinical conditions caused by immune reaction to certain drugs. The allelic variance of human leukocyte antigens of HLA-B*13:01 has been s...

    Authors: Haiqin Jiang, Chuang-Wei Wang, Zhaoxi Wang, Yufei Dai, Yanping Zhu, Yun-Shien Lee, Yang Cao, Wen-Hung Chung, Songying Ouyang and Hongsheng Wang
    Citation: Journal of Biomedical Science 2022 29:58
    Content type: Research Published on:

  2. Due to the difficulties in early diagnosing and treating hepatocellular carcinoma (HCC), prognoses for patients remained poor in the past decade. In this study, we established a screening model to discover nov...

    Authors: Yi-Chieh Yang, Ming-Hsien Chien, Tsung-Ching Lai, Min-Che Tung, Yi-Hua Jan, Wei-Ming Chang, Shih-Ming Jung, Ming-Huang Chen, Chun-Nan Yeh and Michael Hsiao
    Citation: Journal of Biomedical Science 2021 28:29
    Content type: Research Published on:

  4. The development of drug resistance in oral squamous cell carcinoma (OSCC) that frequently leads to recurrence and metastasis after initial treatment remains an unresolved challenge. Presence of cancer stem cel...

    Authors: Te-Hsuan Jang, Wei-Chieh Huang, Shiao-Lin Tung, Sheng-Chieh Lin, Po-Ming Chen, Chun-Yu Cho, Ya-Yu Yang, Tzu-Chen Yen, Guo-Hsuen Lo, Shuang-En Chuang and Lu-Hai Wang
    Citation: Journal of Biomedical Science 2022 29:42
    Content type: Research Published on:

  5. Trauma represents the leading cause of death among young people in industrialized countries. Recent clinical and experimental studies have brought increasing evidence for activation of the innate immune system in...

    Authors: Miriam D Neher, Sebastian Weckbach, Michael A Flierl, Markus S Huber-Lang and Philip F Stahel
    Citation: Journal of Biomedical Science 2011 18:90
    Content type: Review Published on:

  6. Extracellular communication, in other words, crosstalk between cells, has a pivotal role in the survival of an organism. This communication occurs by different methods, one of which is extracellular vesicles. Exo...

    Authors: Howida M. Nail, Chien-Chih Chiu, Chung-Hang Leung, Mahmoud M. M. Ahmed and Hui-Min David Wang
    Citation: Journal of Biomedical Science 2023 30:69
    Content type: Review Published on:

  7. N-linked glycosylation is one of the most abundant posttranslational modifications of membrane-bound proteins in eukaryotes and affects a number of biological activities, including protein biosynthesis, protein.....

    Authors: Ying-Nai Wang, Heng-Huan Lee, Jennifer L. Hsu, Dihua Yu and Mien-Chie Hung
    Citation: Journal of Biomedical Science 2020 27:77
    Content type: Review Published on:

  8. Parkinson’s disease (PD) is the second most common neurodegenerative disease attributed to the synergistic effects of genetic risk and environmental stimuli. Although PD is characterized by motor dysfunction resu...

    Authors: Szu-Ju Chen and Chin-Hsien Lin
    Citation: Journal of Biomedical Science 2022 29:54
    Content type: Review Published on:

  9. Taurine (aminoethane sulfonic acid) is an ubiquitous compound, found in very high concentrations in heart and muscle. Although taurine is classified as an amino acid, it does not participate in peptide bond forma...

    Authors: Stephen W Schaffer, Chian Ju Jong, Ramila KC and Junichi Azuma
    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S2
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  10. The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour suppression. It is frequently inactivated in various tumours. The funct...

    Authors: Linbin Zhou, Danny Siu-Chun Ng, Jason C. Yam, Li Jia Chen, Clement C. Tham, Chi Pui Pang and Wai Kit Chu
    Citation: Journal of Biomedical Science 2022 29:33
    Content type: Review Published on:

  13. Monoclonal antibodies (mAbs) are a major targeted therapy for malignancies, infectious diseases, autoimmune diseases, transplant rejection and chronic inflammatory diseases due to their antigen specificity and lo...

    Authors: Wen-Wei Lin, Yun-Chi Lu, Chih-Hung Chuang and Tian-Lu Cheng
    Citation: Journal of Biomedical Science 2020 27:76
    Content type: Review Published on:

  14. ...mRNA-based drugs have tremendous potential as clinical treatments, however, a major challenge in realizing this drug class will promise to develop methods for safely delivering the bioactive agents with high e...

    Authors: Yu-Shiuan Wang, Monika Kumari, Guan-Hong Chen, Ming-Hsiang Hong, Joyce Pei-Yi Yuan, Jui-Ling Tsai and Han-Chung Wu
    Citation: Journal of Biomedical Science 2023 30:84
    Content type: Review Published on:

  15. Arsenic is a strong stimulus of heme oxygenase (HO)-1 expression in experimental studies in response to oxidative stress caused by a stimulus. A functional GT-repeat polymorphism in the HO-1 gene promoter was ...

    Authors: Meei-Maan Wu, Hung-Yi Chiou, Te-Chang Lee, Chi-Ling Chen, Ling-I Hsu, Yuan-Hung Wang, Wen-Ling Huang, Yi-Chen Hsieh, Tse-Yen Yang, Cheng-Yeh Lee, Ping-Keung Yip, Chih-Hao Wang, Yu-Mei Hsueh and Chien-Jen Chen
    Citation: Journal of Biomedical Science 2010 17:70
    Content type: Research Published on:

  16. Trial Registration...This prospective observational study was approved by the Institutional Review Board of the University of Tokyo and...

    Authors: Nozomi Igarashi, Megumi Honjo, Reiko Yamagishi, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Toshikatsu Kaburaki and Makoto Aihara
    Citation: Journal of Biomedical Science 2021 28:47
    Content type: Research Published on:

  18. Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems. In 3D cell cultures, cancer cell...

    Authors: Waad H. Abuwatfa, William G. Pitt and Ghaleb A. Husseini
    Citation: Journal of Biomedical Science 2024 31:7
    Content type: Review Published on:

  19. Chikungunya virus (CHIKV) is a re-emerging mosquito-borne human pathogen that causes chikungunya fever, which is typically accompanied by severe joint pain. In Asia, serological evidence indicated that CHIKV f...

    Authors: Sarawut Khongwichit, Jira Chansaenroj, Chintana Chirathaworn and Yong Poovorawan
    Citation: Journal of Biomedical Science 2021 28:84
    Content type: Review Published on:

  20. E26 transformation-specific (ETS) transcription variant 5 (ETV5), also known as ETS-related molecule (ERM), exerts versatile functions in normal physiological processes, including branching morphogenesis, neural ...

    Authors: Yi Wei, Shenqi Han, Jingyuan Wen, Jingyu Liao, Junnan Liang, Jingjing Yu, Xiaoping Chen, Shuai Xiang, Zhao Huang and Bixiang Zhang
    Citation: Journal of Biomedical Science 2023 30:17
    Content type: Review Published on:

  21. Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is conside...

    Authors: Camilla J. Williams, Zhixiu Li, Nicholas Harvey, Rodney A. Lea, Brendon J. Gurd, Jacob T. Bonafiglia, Ioannis Papadimitriou, Macsue Jacques, Ilaria Croci, Dorthe Stensvold, Ulrik Wisloff, Jenna L. Taylor, Trishan Gajanand, Emily R. Cox, Joyce S. Ramos, Robert G. Fassett…
    Citation: Journal of Biomedical Science 2021 28:37
    Content type: Research Published on:

  22. Sorafenib is a kinase inhibitor that is used as a first-line therapy in advanced hepatocellular carcinoma (HCC) patients. However, the existence of sorafenib resistance has limited its therapeutic effect. Thro...

    Authors: Tong-tong Li, Jie Mou, Yao-jie Pan, Fu-chun Huo, Wen-qi Du, Jia Liang, Yang Wang, Lan-sheng Zhang and Dong-sheng Pei
    Citation: Journal of Biomedical Science 2021 28:56
    Content type: Research Published on:

  23. The tripartite motif (TRIM) protein family is a highly conserved group of E3 ligases with 77 members known in the human, most of which consist of a RING-finger domain, one or two B-box domains, and a coiled-coil ...

    Authors: Kan Lu, Yonglong Pan, Zhao Huang, Huifang Liang, Ze-yang Ding and Bixiang Zhang
    Citation: Journal of Biomedical Science 2022 29:69
    Content type: Review Published on:

  24. O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a type of glycosylation that occurs when a monosaccharide, O-GlcNAc, is added onto serine or threonine residues of nuclear or cytoplasmic proteins by O-GlcN...

    Authors: Yi-Hsuan Chang, Chia-Lin Weng and Kuo-I Lin
    Citation: Journal of Biomedical Science 2020 27:57
    Content type: Review Published on:

  26. With the advancement of next generation sequencing technologies (NGS), whole-genome sequencing (WGS) has been deployed to a wide range of clinical scenarios. Rapid and accurate classification of drug-resistant My...

    Authors: Ming-Chih Yu, Ching-Sheng Hung, Chun-Kai Huang, Cheng-Hui Wang, Yu-Chih Liang and Jung-Chun Lin
    Citation: Journal of Biomedical Science 2021 28:86
    Content type: Research Published on:

  28. X-linked inhibitor of apoptosis protein (XIAP), survivin, and BRUCE are members of the inhibitor-of-apoptosis protein (IAP) family known for their inhibitory effects on caspase activity and dysregulation of these...

    Authors: Chun Hei Antonio Cheung, Yung-Chieh Chang, Tzu-Yu Lin, Siao Muk Cheng and Euphemia Leung
    Citation: Journal of Biomedical Science 2020 27:31
    Content type: Review Published on:

  29. The COVID-19 pandemic continues to pose a significant worldwide threat to human health, as emerging SARS-CoV-2 Omicron variants exhibit resistance to therapeutic antibodies and the ability to evade vaccination...

    Authors: Hsiao-Ling Chiang, Kang-Hao Liang, Ruei-Min Lu, Ting-Wen Kuo, Yi‑Ling Lin and Han-Chung Wu
    Citation: Journal of Biomedical Science 2023 30:59
    Content type: Research Published on:

  31. Toll-like receptor-3 (TLR-3) is a critical component of innate immune system against dsRNA viruses and is expressed in the central nervous system. However, it remains unknown whether TLR3 may serve as a therap...

    Authors: Jiin-Haur Chuang, Hui-Ching Chuang, Chao-Cheng Huang, Chia-Ling Wu, Yung-Ying Du, Mei-Lang Kung, Chih-Hao Chen, San-Cher Chen and Ming-Hong Tai
    Citation: Journal of Biomedical Science 2011 18:65
    Content type: Research Published on:

  33. In 1889 Dr. John Bland-Sutton, a prominent London surgeon, was consulted about fatal rickets in over 20 successive litters of lion cubs born at the London Zoo. He evaluated the diet and found the cause of rick...

    Authors: Russell W Chesney and Gail Hedberg
    Citation: Journal of Biomedical Science 2010 17(Suppl 1):S36
    Content type: Review Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  38. 5-methoxytryptophan (5-MTP) is an endothelial factor with anti-inflammatory properties. It is synthesized from L-tryptophan via two enzymatic steps: tryptophan hydroxylase-1 (TPH-1) and hydroxyindole O-methylt...

    Authors: Kenneth K. Wu, Cheng-Chin Kuo, Shaw-Fang Yet, Chii-Ming Lee and Jun-Yang Liou
    Citation: Journal of Biomedical Science 2020 27:79
    Content type: Review Published on:

  39. Tumor suppressors are frequently downregulated in human cancers and understanding of the mechanisms through which tumor cells restrict the expression of tumor suppressors is important for the prognosis and int...

    Authors: Ruey-Hwa Chen, Yu-Ru Lee and Wei-Chien Yuan
    Citation: Journal of Biomedical Science 2012 19:81
    Content type: Review Published on:

  40. Picornaviruses cause several diseases, not only in humans but also in various animal hosts. For instance, human enteroviruses can cause hand-foot-and-mouth disease, herpangina, myocarditis, acute flaccid paralysi...

    Authors: Jing-Yi Lin, Tzu-Chun Chen, Kuo-Feng Weng, Shih-Cheng Chang, Li-Lien Chen and Shin-Ru Shih
    Citation: Journal of Biomedical Science 2009 16:103
    Content type: Review Published on:

  41. Dengue is becoming recognized as one of the most important vector-borne human diseases. It is predominant in tropical and subtropical zones but its geographical distribution is progressively expanding, making ...

    Authors: Jih-Jin Tsai, Kulkanya Chokephaibulkit, Po-Chih Chen, Li-Teh Liu, Hui-Mien Hsiao, Yu-Chih Lo and Guey Chuen Perng
    Citation: Journal of Biomedical Science 2013 20:88
    Content type: Review Published on:

  42. The developments of antibodies for cancer therapeutics have made remarkable success in recent years. There are multiple factors contributing to the success of the biological molecule including origin of the antib...

    Authors: Mukesh Kumar, Akansha Jalota, Sushil Kumar Sahu and Shabirul Haque
    Citation: Journal of Biomedical Science 2024 31:6
    Content type: Review Published on:

  44. The human gut is home to complex microbial populations that change dynamically in response to various internal and external stimuli. The gut microbiota provides numerous functional benefits that are crucial for h...

    Authors: Pey Yee Lee, Siok-Fong Chin, Hui-min Neoh and Rahman Jamal
    Citation: Journal of Biomedical Science 2017 24:36
    Content type: Review Published on:

  45. Upon EV-A71 infection of a host cell, EV-A71 RNA is translated into a viral polyprotein. Although EV-A71 can use the cellular translation machinery to produce viral proteins, unlike cellular translation, which is...

    Authors: Ming-Chih Lai, Han-Hsiang Chen, Peng Xu and Robert Y. L. Wang
    Citation: Journal of Biomedical Science 2020 27:22
    Content type: Review Published on:

  46. Cancer metastasis is the major cause of mortality in cancer cases and is responsible for cancer deaths. It is known that cancer cells communicate with surrounding microenvironmental cells, such as fibroblast cell...

    Authors: Akiko Kogure, Nobuyoshi Kosaka and Takahiro Ochiya
    Citation: Journal of Biomedical Science 2019 26:7
    Content type: Review Published on:

  47. Helicobacter pylori infection is the principal cause of peptic ulcer disease, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue lymphoma. Recent studies have shown that it may interfere with ma...

    Authors: Feng-Woei Tsay and Ping-I Hsu
    Citation: Journal of Biomedical Science 2018 25:65
    Content type: Review Published on:

  48. Vasoactive intestinal peptide (VIP) plays important roles in many biological functions, such as, stimulation of contractility in the heart, vasodilation, promoting neuroendocrine-immune communication, lowering ar...

    Authors: Wei Jiang, Hua Wang, Yu-sheng Li and Wei Luo
    Citation: Journal of Biomedical Science 2016 23:63
    Content type: Review Published on:

  49. Gut microbiota interacting with an intact mucosal surface are key to the maintenance of homeostasis and health. This review discusses the current state of knowledge of ... abundance and diversity, the aim of the

    Authors: Andre Gerald Buret, Jean-Paul Motta, Thibault Allain, Jose Ferraz and John Lawrence Wallace
    Citation: Journal of Biomedical Science 2019 26:1
    Content type: Review Published on:

  50. Hepatoblastoma, a leading primary hepatic malignant tumor in children, is originated from primitive hepatic stem cells. We aimed to elucidate the relationships between the histological distribution of β-cateni...

    Authors: Jia-Feng Wu, Hsiu-Hao Chang, Meng-Yao Lu, Shiann-Tarng Jou, Kai-Chi Chang, Yen-Hsuan Ni and Mei-Hwei Chang
    Citation: Journal of Biomedical Science 2017 24:62
    Content type: Research Published on:
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Journal of Biomedical Science

ISSN: 1423-0127